62692-57-3Relevant academic research and scientific papers
Reductive Coupling between C-N and C-O Electrophiles
He, Rong-De,Li, Chun-Ling,Pan, Qiu-Quan,Guo, Peng,Liu, Xue-Yuan,Shu, Xing-Zhong
supporting information, p. 12481 - 12486 (2019/09/04)
The cross-electrophile reaction is a promising strategy for C-C bond formation. Recent studies have focused mainly on reactions with organic halides. Here we report a coupling reaction between C-N and C-O electrophiles that demonstrates the possibility of constructing a C-C bond via C-N and C-O cleavage. Several reactions between benzyl/aryl ammonium salts and vinyl/aryl C-O electrophiles have been studied. Preliminary mechanistic studies revealed that the benzyl ammoniums were activated through a radical mechanism.
Allylic oxidations of terminal olefins using a palladium thioether catalyst
Henderson, William H.,Check, Christopher T.,Proust, Nicolas,Stambuli, James P.
supporting information; experimental part, p. 824 - 827 (2010/04/06)
"Chemical equation presented" A palladium catalyst that converts terminal olefins to linear allylic acetates at lower catalyst loadings and faster reaction times than current systems is reported. This reaction can be conducted using benzoquinone as the oxidizing agent or catalytic amounts of copper and hydroquinone under one atmosphere of oxygen. Preliminary reactivity studies of π-allylpalladium complexes under our reaction conditions do not provide results similar to those obtained in the catalytic reaction, which may suggest an alternative reaction pathway. The palladium catalyst is ligated by an aryloxyalkyl aryl sulfide, which is identified as a new ligand for homogeneous catalysis.
Asymmetric hydrogenation of acyclic enol esters
Boaz, Neil W.
, p. 5505 - 5508 (2007/10/03)
High enantioselectivity has been observed for the catalytic asymmetric hydrogenation of enol esters bearing a vinylic (≤94% ee) or acetylenic (>97% ee) substituent using a rhodium-chiral bisphosphine catalyst. This is at variance with the hydrogenation of enol esters bearing a saturated substituent, which are hydrogenated with only moderate enantioselectivity under the same conditions.
