62693-41-8Relevant academic research and scientific papers
Oxadiazoline derivatives
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, (2008/06/13)
Benzylidenehydrazono-oxadiazoline compounds have been prepared of the formula: STR1 wherein R1 and R2 are both lower alkyl or form with the heterocyclic ring carbon atom an alicyclic ring; and R3 when present is selected from halogen, lower alkyl and lower alkoxy. The preparation involves condensing a benzaldehyde with carbodihydrazide and further condensing with a ketone (or vice versa) to form the corresponding crossed carbodihydrazone, and oxidizing and cyclizing to form the oxadiazoline derivatives. These derivatives have analgesic and/or anti-inflammatory activity.
