627-75-8

Basic information

• Product Name: D-(-)-Arginine hydrochloride
• Synonyms: monohydrochloride,d-arginin;H-D-ARG-OH HCL;D-2-AMINO-5-GUANIDINOVALERIC ACID HYDROCHLORIDE;D-ARGININE HCL;D(-)-ARGININE HYDROCHLORIDE;D-ARGININE HYDROCHLORIDE;D-ARGININE MONOHYDROCHLORIDE;D-Arg-OH HCl
• CAS NO: 627-75-8
• Molecular Formula: C₆H₁₄N₄O₂*2ClH
• Molecular Weight: 210.66
• EINECS: 211-010-1
• Product Categories: AMINO ACIDS;Arginine Metabolism;ArginineNitric Oxide and Cell Stress;Amino Acid Derivatives;Nitric Oxide Metabolism;Peptide Synthesis
• Mol File: 627-75-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: 216-218 °C(lit.)
• Boiling Point: 409.1 °C at 760 mmHg
• Flash Point: 201.2 °C
• Appearance: White crystalline powder
• Vapor Pressure: 7.7E-08mmHg at 25°C
• Storage Temp.: Store at RT.
• Water Solubility: Soluble in water (50 mg/ml), and 3N HCl (5).
• BRN: 5773432
• CAS DataBase Reference: D-(-)-Arginine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: D-(-)-Arginine hydrochloride(627-75-8)
• EPA Substance Registry System: D-(-)-Arginine hydrochloride(627-75-8)

Safety Data

• Statements: 20/22
• Safety Statements: 22-24/25
• WGK Germany: 3
• RTECS: CF1995000
• TSCA: Yes
• Hazardous Substances Data: 627-75-8(Hazardous Substances Data)

Usage

Chemical Properties

WHITE CRYSTALLINE POWDER

Uses

Different sources of media describe the Uses of 627-75-8 differently. You can refer to the following data:
1. The influence in creatinine metabolismis that by that d-arginine monohydrochloride caused slightly larger increases in muscle creatine. D-Arginyl ethyl ester was synthesized by vigorously stirring D-arginine monohydrochloride and excess anhydrous ethanol in an ice bath.
2. D-arginine attenuates increased arginase expression, oxidative stress, endothelial dysfunction, and advanced glycation endproducts formation induced by methylgloxyl and high glucose. This attenuation by D-arginine is thought to occur through an endothelial NOS independent mechanism.

InChI:InChI=1/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m1./s1

Upstream product

• 1233718-15-4 trivanchrobactin 

Downstream Products

• 128425-11-6 C₁₅H₂₂N₈O₇ 
• 22888-59-1 L-arginine methyl ester dihydrochloride 
• 2389-86-8 (2R)-2-acetamido-5-guanidino-pentanoate 
• 117922-52-8 Tos-Cys(Bzl)-Tyr-Phe-Gln-Asn-Cys(Bzl)-Pro-Arg-NH₂ 
• 35752-61-5 Z-Ala-D-Arg 
• 66036-77-9 Nω-nitro-D-arginine 
• 141968-19-6 N^ω-nitro-D-arginine methyl ester 
• 2279-08-5 Z-D-Arg(NO₂)-OH 

Relevant articles and documents

Ruckerbactin Produced by Yersinia ruckeri YRB Is a Diastereomer of the Siderophore Trivanchrobactin Produced by Vibrio campbellii DS40M4

The Gram-negative bacterium Yersinia ruckeri is the causative agent for enteric red mouth disease in salmonids. The genome of Y. ruckeri YRB contains a biosynthetic gene cluster encoding the biosynthesis of catechol siderophores that are diastereomeric with the known vanchrobactin class of siderophores, (DHBDArgLSer)(1–3). Ruckerbactin (1), produced by Y. ruckeri YRB, was found to be the linear tris-l-serine ester composed of l-arginine and 2,3-dihydroxybenzoic acid, (DHBLArgLSer)3. The biscatechol, (DHBLArgLSer)2 (2), and monocatechol, DHBLArgLSer (3), compounds were also isolated and characterized. The macrolactone of ruckerbactin was not detected. The presence of LArg in ruckerbactin makes it the diastereomer of trivanchrobactin with DArg. The electronic circular dichroism spectra of Fe(III)–ruckerbactin and Fe(III)–trivanchrobactin reveal the opposite enantiomeric configurations at the Fe(III) sites. Fe(III)–ruckerbactin adopts the Δ configuration, and Fe(III)–trivanchrobactin adopts the Λ configuration. Y. ruckeri YRB was also found to produce the antimicrobial agent holomycin (4).