627-85-0Relevant academic research and scientific papers
Structure and origin of artifacts in the analysis of plasmalogens
Dudda, Angela,Spiteller, Gerhard
, p. 303 - 308 (2007/10/03)
The determination of aldehydic compounds was achieved by gas chromatographic/mass spectrometric analysis of derived thioacetals. These were produced, together with artifacts, in a one-step reaction when plasmalogens were treated with ethane-1,2-dithiol and BF3. The artifacts Were recognized to be 2-alkylidene-1,3-dithiolanes derived from phospholipids. The latter were converted by BP, treatment into diacylglycerols, which were transformed in a complicated reaction into 2-alkyl-2-((2-mercaptoethyl)thiol-1,3-dithiolane. These compounds were decomposed thermally, e.g. in the injector of a gas chromatograph, in 2-alkylidene-1,3-dithiolanes, This reaction is not restricted to phospholipids but occurs with all monoacylated glycols.
