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Usage

Uses

Used in Pharmaceutical Industry:
(R)-2-hydroxy-2-phenylpropyl 4-methylbenzenesulfonate is used as an intermediate for the production of pharmaceuticals and other organic compounds. Its unique structure allows it to be a key component in the synthesis of various drugs.
Used as a Stabilizer and Preservative:
(R)-2-hydroxy-2-phenylpropyl 4-methylbenzenesulfonate is used as a stabilizer and preservative in various products due to its ability to inhibit the growth of microorganisms. This makes it a valuable additive for the food and beverage industry, as well as for cosmetics and personal care products.
Used in Polymer and Specialty Chemicals Manufacturing:
(R)-2-hydroxy-2-phenylpropyl 4-methylbenzenesulfonate may also have applications in the manufacturing of polymers and specialty chemicals. Its unique properties can contribute to the development of new materials with specific characteristics, such as improved stability or enhanced performance in certain conditions.
Overall, (R)-2-hydroxy-2-phenylpropyl 4-methylbenzenesulfonate is a versatile chemical compound with potential applications in multiple industries, including pharmaceuticals, food and beverages, cosmetics, and polymer manufacturing.

Upstream product

• 2406-23-7 (R)-ethyl 2-hydroxy-2-phenylpropanoate 
• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 1603-79-8 phenylglyoxylic acid ethyl ester 
• 13448-80-1 methyl R-(-)-atrolactate 
• 2406-22-6 (R)-1-phenyl-1,2-ethanediol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 2085-88-3 (R)-2-methyl-2-phenyloxirane 
• 17643-24-2 (R)-1-amino-2-phenylpropan-2-ol 
• 53777-08-5 (S)-2-phenyl-butan-2-ol 

Relevant academic research and scientific papers

Absolute stereochemical determination of 1,2-diols via complexation with dinaphthyl borinic acid

Rapid derivatization of chiral 1,2-diols with dinaphthyl borinic acid (DBA) leads to a cyclic boronate, enabling the absolute stereochemical prediction via exciton-coupled circular dichroic (ECCD) of the naphthyl groups. Aryl- and alkyl-substituted 1,2-diols derivatized with DBA yield a predictable ECCD, which is also in agreement with theoretical predictions derived from computationally minimized structures.

Highly homogeneous stereocontrolled construction of quaternary hydroxyesters by addition of dimethylzinc to α-ketoesters promoted by chiral perhydrobenzoxazines and B(OEt)3

A highly efficient enantioselective addition of Me2Zn to α-ketoesters, assisted by a chiral perhydro-1,3-benzoxazine ligand, is described. This novel catalytic system offers homogeneous elevated enantioselectivities in the preparation of α-hydroxyesters that bear a quaternary stereocenter, with a minor dependence on electronic and steric effects when aromatic, heteroaromatic, or aliphatic α-ketoesters are employed. The catalyst can be recovered and reused without loss of activity.

A concise synthesis of (S)-(+)-1-(4-{2-[bis-(4-fluorophenyl)methoxy]-ethyl} piperazin-1-yl)-2-phenylpropan-2-ol dimaleate

(S)-(+)-1-(4-{2-[Bis-(4-fluorophenyl)methoxy]-ethyl}piperazin-1-yl) -2-phenylpropan-2-ol dimaleate was prepared in several steps from (S)-(+)-atrolactic acid by a process permitting synthesis of multigram quantities. With the information provided by asymmetric synthesis, the X-ray crystal structure was solved.