627077-82-1Relevant articles and documents
Geraniol-derived 1,2,4-trioxanes with potent in-vivo antimalarial activity
Singh, Chandan,Gupta, Nitin,Puri, Sunil K.
, p. 3447 - 3450 (2003)
Geraniol, an abundantly available naturally occurring allylic alcohol, has been used as a starting material to prepare a series of 6-[α-(3′ -aryl-3′-hydroxypropyl)vinyl]-1,2,4-trioxanes. Some of these novel trioxanes have shown very promising antimalarial
Synthesis of new 6-alkylvinyl/arylalkylvinyl substituted 1,2,4-trioxanes active against multidrug-resistant malaria in mice
Singh, Chandan,Gupta, Nitin,Puri, Sunil K.
, p. 5553 - 5562 (2007/10/03)
3-Alkyl/arylalkyl substituted 2-butenols 9, 10, 23a-d undergo regiospecific photooxygenation to furnish β-hydroxyhydroperoxides 11, 12, 24a-d, respectively, in reasonable yields. Acid catalyzed condensation of 11, 12, 24a-d with various ketones furnish ne