62715-76-8

Basic information

• Product Name: 7-Benzothiazolol,2-amino-(9CI)
• Synonyms: 7-Benzothiazolol,2-amino-(9CI);2-amino-1,3-benzothiazol-7-ol;2-Aminobenzo[d]thiazol-7-ol;2-Amino-7-hydroxybenzothiazole;7-BENZOTHIAZOLOL, 2-AMINO-
• CAS NO: 62715-76-8
• Molecular Formula: C₇H₆N₂OS
• Molecular Weight: 166.2
• Product Categories: BENZOTHIAZOLE
• Mol File: 62715-76-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 394.6±34.0 °C(Predicted)
• Appearance: /
• Density: 1.553±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 8.21±0.40(Predicted)
• CAS DataBase Reference: 7-Benzothiazolol,2-amino-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Benzothiazolol,2-amino-(9CI)(62715-76-8)
• EPA Substance Registry System: 7-Benzothiazolol,2-amino-(9CI)(62715-76-8)

Safety Data

• Hazardous Substances Data: 62715-76-8(Hazardous Substances Data)

Usage

General Description

7-Benzothiazolol, 2-amino-(9CI) is a chemical compound with the molecular formula C8H7N2S. It is a type of benzothiazole derivative, which is commonly used in the synthesis of pharmaceuticals, dyes, and pesticide intermediates. The compound has a benzene ring fused to a thiazole ring, and a primary amino group attached to the second carbon atom of the thiazole ring. 7-Benzothiazolol,2-amino-(9CI) has potential applications in the development of drugs and other bioactive compounds due to its pharmacological properties. Additionally, it can be used in organic chemistry as a versatile building block for various synthetic reactions. However, it is important to handle this chemical with care, as it may pose health hazards if not properly managed and stored.

Upstream product

• 3394-05-6 N-(3-hydroxyphenyl)thiourea 
• 51-81-0 3-aminophenol hydrochloride 

Downstream Products

• 1309261-63-9 3-(7-hydroxy-1,3-benzothiazol-2-yl)-2-phenylquinazolin-4(3H)-one 
• 1309261-81-1 C₂₁H₁₄N₄O₂S 

Relevant articles and documents

QSAR modeling of synthesized 3-(1,3-benzothiazol-2-yl) 2-phenyl quinazolin-4(3H)-ones as potent antibacterial agents

Present communication elicits the designing and synthesis of 3-(1,3-benzothiazol-2-yl) 2-phenyl quinazolin-4(3H)-ones as potential antibacterial agents. A number of substituted 2-amino benzothiazoles, 2-amino-5-[(E)-phenyl diazenyl] benzoic acid, and 2-phenyl-4H benzo[d] [1,3] oxazin-4-one were synthesized as the precursor substrates. The compounds were synthesized in excellent yields and the structures were corroborated on the basis of IR, 1H NMR, Mass, and elemental analysis data. These compounds were screened in vitro for their antibacterial activity against a representative panel of Gram positive and Gram negative bacteria and models were generated through quantitative structure-activity relationship (QSAR).The activity contributions due to structural and substituent effects were determined using sequential regression procedure. The antimicrobial assay data show that the synthesized compounds are found to manifest profound antimicrobial activity. Springer Science+Business Media, LLC 2011.