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(1E)-2,3,4,5-tetrahydroxypentanal oxime, also known as non-preferred name, is an oxime derivative of pentanal with four hydroxyl groups attached to the carbon chain. It is a versatile and valuable chemical compound with potential applications in various fields.
Used in Coordination Chemistry:
(1E)-2,3,4,5-tetrahydroxypentanal oxime (non-preferred name) is used as a chelating agent for the formation of coordination compounds. Its ability to form stable complexes with metal ions makes it a useful tool in this field.
Used in Pharmaceutical Industry:
(1E)-2,3,4,5-tetrahydroxypentanal oxime (non-preferred name) is used as a precursor for the synthesis of various drugs. Its unique structure allows for the development of new pharmaceutical compounds with potential therapeutic applications.
Used in Chemical Analysis:
(1E)-2,3,4,5-tetrahydroxypentanal oxime (non-preferred name) is used as a reagent in chemical analysis. Its properties make it suitable for use in various analytical techniques, aiding in the identification and quantification of substances.
Used in Medicine:
(1E)-2,3,4,5-tetrahydroxypentanal oxime (non-preferred name) has potential applications in medicine, where it can be utilized in the development of new drugs and therapies.
Used in Agriculture:
(1E)-2,3,4,5-tetrahydroxypentanal oxime (non-preferred name) can be used in agriculture, potentially in the development of new agrochemicals or as a component in the synthesis of bioactive compounds for crop protection.
Used in Materials Science:
(1E)-2,3,4,5-tetrahydroxypentanal oxime (non-preferred name) has potential applications in materials science, where it may be used in the development of new materials with unique properties.

6272-50-0

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6272-50-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6272-50-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,7 and 2 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 6272-50:
(6*6)+(5*2)+(4*7)+(3*2)+(2*5)+(1*0)=90
90 % 10 = 0
So 6272-50-0 is a valid CAS Registry Number.

6272-50-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (5E)-5-hydroxyiminopentane-1,2,3,4-tetrol

1.2 Other means of identification

Product number -
Other names D-Riboseoxim

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6272-50-0 SDS

6272-50-0Relevant academic research and scientific papers

Synthesis and biological evaluation of new carbohydrate-substituted indenoisoquinoline topoisomerase I inhibitors and improved syntheses of the experimental anticancer agents indotecan (LMP400) and indimitecan (LMP776)

Beck, Daniel E.,Agama, Keli,Marchand, Christophe,Chergui, Adel,Pommier, Yves,Cushman, Mark

, p. 1495 - 1512 (2014/03/21)

Carbohydrate moieties were strategically transported from the indolocarbazole topoisomerase I (Top1) inhibitor class to the indenoisoquinoline system in search of structurally novel and potent Top1 inhibitors. The syntheses and biological evaluation of 20 new indenoisoquinolines glycosylated with linear and cyclic sugar moieties are reported. Aromatic ring substitution with 2,3-dimethoxy-8,9-methylenedioxy or 3-nitro groups exerted strong effects on antiproliferative and Top1 inhibitory activities. While the length of the carbohydrate side chain clearly correlated with antiproliferative activity, the relationship between stereochemistry and biological activity was less clearly defined. Twelve of the new indenoisoquinolines exhibit Top1 inhibitory activity equal to or better than that of camptothecin. An advanced synthetic intermediate from this study was also used to efficiently prepare indotecan (LMP400) and indimitecan (LMP776), two anticancer agents currently under investigation in a Phase I clinical trial at the National Institutes of Health.

A derivatization procedure for the simultaneous analysis of iminosugars and other low molecular weight carbohydrates by GC-MS in mulberry (Morus sp.)

Rodríguez-Sánchez,Hernández-Hernández,Ruiz-Matute,Sanz

experimental part, p. 353 - 359 (2011/09/12)

Different derivatization procedures were assayed to simultaneously analyse iminosugars such as deoxynojirimycin (DNJ) or fagomine and other carbohydrates of low molecular weight by gas chromatography coupled to mass spectrometry (GC-MS) in Morus sp. Both oximation + trimethylsilylation and oximation + acetylation allowed the separation of target compounds, whereas trimethylsilyl (TMS) and acetylated derivatives showed several coelutions. Nevertheless, oximation + acetylation were discarded for giving inaccurate results for ketoses due to their incomplete derivatization. Different conditions for the conversion into trimethylsilyl oximes (TMSO) were assayed, the best results being achieved using hexamethyldisilazane with trifluoroacetic acid as silylation agent. Contents of iminosugars (DNJ, fagomine and pipecolic acid derivatives) and other carbohydrates such as mono and disaccharides, myo-inositol and galactinol isomers in mulberry extracts (fruits, leaves and branches) were determined by GC-MS using the TMSO procedure.

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