62724-32-7Relevant articles and documents
Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment
Kaur, Navdeep,Fang, Yao-Ching,Lee, Hsueh-Yun,Singh, Arshdeep,Nepali, Kunal,Lin, Mei-Hsiang,Yeh, Teng-Kuang,Lai, Mei-Jung,Chan, Lung,Tu, Yong-Kwang,Banerjee, Suddhasatwa,Hu, Chaur-Jong,Liou, Jing-Ping
, (2020)
A series of 10,11-dihydro-5H-dibenzo [b,f]azepine hydroxamates (4–15) were synthesized, behaving as histone deacetylase inhibitors, and examined for their influence on vascular cognitive impairment (VCI), which correlated with dementia. The results reveal
HECT E3 LIGASE INHIBITORS AND USES THEREOF
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Page/Page column 49, (2020/12/29)
The present invention relates to tricyclic derivatives of formula (I), which are useful as inhibitors of HECT-domain-containing E3 ligases, in particular NEDD4. The present invention also refers to pharmaceutical compositions comprising compounds of formu