6273-71-8

Basic information

• Product Name: 6-methoxy-4-phenyl-1,2-dihydronaphthalene
• CAS NO: 6273-71-8
• Molecular Formula: C₁₇H₁₆O
• Molecular Weight: 236.3083
• Mol File: 6273-71-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 366.8°C at 760 mmHg
• Flash Point: 146.8°C
• Density: 1.095g/cm³
• Vapor Pressure: 3.02E-05mmHg at 25°C
• Refractive Index: 1.599
• CAS DataBase Reference: 6-methoxy-4-phenyl-1,2-dihydronaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methoxy-4-phenyl-1,2-dihydronaphthalene(6273-71-8)
• EPA Substance Registry System: 6-methoxy-4-phenyl-1,2-dihydronaphthalene(6273-71-8)

Safety Data

• Hazardous Substances Data: 6273-71-8(Hazardous Substances Data)

Upstream product

• 6836-19-7 7-Methoxy-1-tetralone 
• 108-86-1 bromobenzene 

Downstream Products

• 22117-49-3 7-methoxy-1-phenyl-1,2,3,4-tetrahydronaphthalene 
• 368883-84-5 6-methoxy-4-phenyl-3,4-dihydronaphthalen-1(2H)-one 
• 78239-13-1 6-bromo-7-methoxy-1-phenyl-1,2,3,4-tetrahydronaphthalene 
• 27331-38-0 7-methoxy-1-phenylnaphthalene 

Relevant articles and documents

Exploring the synthetic potential of a marine transaminase including discrimination at a remote stereocentre

The marine transaminase, P-ω-TA, can be employed for the transamination from 1-aminotetralins and 1-aminoindanes with differentiation of stereochemistry at both the site of reaction and at a remote stereocentre resulting in formation of ketone products with up to 93% ee. While 4-substituents are tolerated on the tetralin core, the presence of 3- or 8-substituents is not tolerated by the transaminase. In general P-ω-TA shows capacity for remote diastereoselectivity, although both the stereoselectivity and efficiency are dependent on the specific substrate structure. Optimum efficiency and selectivity are seen with 4-haloaryl-1-aminotetralins and 3-haloaryl-1-aminoindanes, which may be associated with the marine origin of this enzyme. This journal is