6274-27-7

Usage

Uses

Used in Agriculture:
2,5-Dichlorophenylthioglycolic acid is used as a herbicide for controlling the growth of undesirable plants and weeds. It functions by disrupting the synthesis of auxin, a plant hormone essential for the regulation of plant growth.
Used in Research and Industrial Applications:
In addition to its agricultural uses, 2,5-dichlorophenylthioglycolic acid is also utilized in research and industrial settings. Its unique properties make it valuable for various applications, although the specific uses in these fields are not detailed in the provided materials.
Caution:
It is important to handle 2,5-dichlorophenylthioglycolic acid with care, as it may have adverse effects on human health and the environment. Proper safety measures should be taken during its use to minimize potential risks.

Upstream product

• 5858-18-4 2,5-dichlorbenzenethiol 
• 79-11-8 chloroacetic acid 
• 68-11-1 mercaptoacetic acid 
• 5402-73-3 2,5-dichlorobenzenesulphonyl chloride 
• 106-46-7 para-dichlorobenzene 
• 33663-41-1 2,5-dichloroaniline hydrochloride 
• 79-08-3 bromoacetic acid 

Downstream Products

• 115893-61-3 (2,5-dichloro-phenylsulfanyl)-acetic acid amide 
• 14295-43-3 4,7,4',7'-tetrachloro-[2,2']bi[benzo[b]thiophenylidene]-3,3'-dione 
• 181375-13-3 (6-R-trans)-3-(chloromethyl)-7-[[[(2,5-dichlorophenyl)thio]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, diphenylmethyl ester 
• 1370637-75-4 C₃₀H₂₅Cl₃N₂O₆S 

Relevant academic research and scientific papers

Synthesis and anti-MRSA activity of novel cephalosporin derivatives

Cephalosporin derivatives containing a unique combination of lipophilic C-7 sidechains and polar C-3 thiopyridinium groups were synthesized and found to exhibit potent anti-MRSA activity in vitro and in vivo. The optimum C-7 sidechains utilized were 2,5-dichlorophenylthioacetamido and 2,6-dichloropyrid-4-ylthioacetamido. The C-3 thiopyridinium rings were substituted at nitrogen with amino acid and pyruvic acid groups that were designed to confer aqueous solubility as required for IV formulation. This paper describes the characteristics of these novel cephalosporins and highlights synthetic methods developed to allow their practical, large-scale syntheses. (C) 2000 Elsevier Science Ltd.

Synthesis and structure-activity relationship of C-3 benzoyloxymethyl cephalosporins exhibiting anti-MRSA activities

A series of cephalosporins bearing C-3 benzoyloxymethyl groups were prepared and evaluated for their anti-MRSA activity and plasma stability. They exhibit excellent in vitro activity (MIC = 0.06 ~ 2 μg/mL) against MRSA and excellent stability in human plasma.