627461-52-3

Upstream product

• 287400-86-6 (4R,6R,7S,11R)methyl 2,6-anhydro-5,9,11,13,14,15-hexadeoxy-10-O-[(1,1-dimethylethyl)dimethylsilyl]-3,4,7-tris-O-[(4-methoxyphenyl)methyl]-5,11-dimethyl-α-D-xylo-D-threo-L-gulo-8-hexadeculo-8,12-pyranoside 
• 627461-48-7 (S)-bromo-4-tert-butyldimethylsiloxy-5-triethylsiloxy-1-pentene 
• 627461-51-2 (S)-4-bromo-2-(tert-butyldimethylsilanyloxy)pent-4-en-1-ol 
• 627461-50-1 (+)-(2S)-4-pentyne-1,2-diol 
• 627461-49-8 2,2-Dimethyl-propionic acid (5R,6R,10S)-10-[(2R,3R,4R,5S,6R)-4,5-bis-(4-methoxy-benzyloxy)-3-methyl-6-triisopropylsilanyloxymethyl-tetrahydro-pyran-2-yl]-7-hydroxy-10-(4-methoxy-benzyloxy)-6-methyl-9-oxo-5-triethylsilanyloxy-decyl ester 
• 287400-85-5 2,2-dimethyl-propionic acid 4-[6-[[4,5-bis-(4-methoxy-benzyloxy)-3-methyl-6-triisopropylsilanyloxymethyl-tetrahydro-pyran-2-yl]-(4-methoxy-benzyloxy)-methyl]-4-(tert-butyl-dimethyl-silanyloxy)-6-methoxy-3-methyl-tetrahydro-pyran-2-yl]-butyl ester 
• 287400-82-2 (4R,6R,7S,11R)-16-(2,2-dimethylpropanoate)methyl 2,6-anhydro-5,9,11,13,14,15-hexadeoxy-3,4,7-tris-O-[(4-methoxyphenyl)methyl]-5,11-dimethyl-1-O-[tris(1-methylethyl)silyl]-α-D-lyxo-D-threo-L-gulo-8-hexadeculo-8,12-pyranoside 
• 287400-84-4 (4R,6R,7S,11R)-16-(2,2-dimethylpropanoate)methyl 2,6-anhydro-5,9,11,13,14,15-hexadeoxy-3,4,7-tris-O-[(4-methoxyphenyl)methyl]-5,11-dimethyl-1-O-[tris(1-methylethyl)silyl]-α-D-xylo-D-threo-L-gulo-8-hexadeculo-8,12-pyranoside 
• 287400-83-3 2,2-Dimethyl-propionic acid 4-{(2R,3S,6R)-6-[(S)-[(2R,3R,4R,5S,6R)-4,5-bis-(4-methoxy-benzyloxy)-3-methyl-6-triisopropylsilanyloxymethyl-tetrahydro-pyran-2-yl]-(4-methoxy-benzyloxy)-methyl]-6-methoxy-3-methyl-4-oxo-tetrahydro-pyran-2-yl}-butyl ester 
• 287400-71-9 (S)-1-[(2R,3R,4R,5S,6R)-4,5-Bis-(4-methoxy-benzyloxy)-3-methyl-6-triisopropylsilanyloxymethyl-tetrahydro-pyran-2-yl]-1-(4-methoxy-benzyloxy)-propan-2-one 
• 287400-80-0 [2S,3R]-2-methyl-3-[(triethylsilyl)oxy]-6-trimethylacetoxy-heptanal 
• 162872-61-9 (S)-2,2-dimethylpropanoic acid 2-hydroxypent-4-ynyl ester 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 994-30-9 triethylsilyl chloride 

Relevant academic research and scientific papers

Multigram Synthesis of the C29-C51 Subunit and Completion of the Total Synthesis of Altohyrtin C (Spongistatin 2)

A multigram synthesis of the C29-C51 subunit of altohyrtin C (spongistatin 2) has been accomplished. Union of this intermediate with the C1-C28 fragment and further elaboration furnished the natural product. Completion of the C29-C51 subunit began with th