627469-49-2Relevant articles and documents
Efficient syntheses of 2-fluoroalkylbenzimidazoles and -benzothiazoles
René, Olivier,Souverneva, Alexandra,Magnuson, Steven R.,Fauber, Benjamin P.
, p. 201 - 204 (2013)
We report an efficient one-step route to 2-fluoroalkylbenzimidazoles and -benzothiazoles via the condensation of fluorinated carboxylic acids and aromatic diamines or aminothiophenols. Additionally, we describe the syntheses of fluoroalkyl-azabenzimidazoles, -purines, and -imidazolopyrazines. This method is high-yielding with broad scope and is operationally simple with potential application to parallel synthesis.