627469-68-5 Usage
Chemical structure
Benzimidazole derivative with a cyclohexyl and methyl substituent
Pharmacological activities
Potential applications in the pharmaceutical industry
Biological pathways
May impact various biological pathways
Therapeutic properties
Of interest for its potential therapeutic properties
Research status
Further research is needed to fully understand the effects and applications of 1-Cyclohexyl-2-methyl-1H-benzoimidazol-5-ylamine
Check Digit Verification of cas no
The CAS Registry Mumber 627469-68-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,2,7,4,6 and 9 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 627469-68:
(8*6)+(7*2)+(6*7)+(5*4)+(4*6)+(3*9)+(2*6)+(1*8)=195
195 % 10 = 5
So 627469-68-5 is a valid CAS Registry Number.
627469-68-5Relevant academic research and scientific papers
Novel benzimidazole-based MCH R1 antagonists
Carpenter, Andrew J.,Al-Barazanji, Kamal A.,Barvian, Kevin K.,Bishop, Michael J.,Britt, Christy S.,Cooper, Joel P.,Goetz, Aaron S.,Grizzle, Mary K.,Hertzog, Donald L.,Ignar, Diane M.,Morgan, Ronda O.,Peckham, Gregory E.,Speake, Jason D.,Swain, Will R.
, p. 4994 - 5000 (2007/10/03)
The identification of an MCH R1 antagonist screening hit led to the optimization of a class of benzimidazole-based MCH R1 antagonists. Structure-activity relationships and efforts to optimize pharmacokinetic properties are detailed along with the demonstration of the effectiveness of an MCH R1 antagonist in an animal model of obesity.
