627510-87-6

Basic information

• Product Name: 3-nitro-4-{(E)-2-[4-(trifluoromethyl)phenyl]ethenyl}pyridine
• Synonyms: 3-nitro-4-{(E)-2-[4-(trifluoromethyl)phenyl]ethenyl}pyridine
• CAS NO: 627510-87-6
• Molecular Weight: 294.233
• Mol File: 627510-87-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-nitro-4-{(E)-2-[4-(trifluoromethyl)phenyl]ethenyl}pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-nitro-4-{(E)-2-[4-(trifluoromethyl)phenyl]ethenyl}pyridine(627510-87-6)
• EPA Substance Registry System: 3-nitro-4-{(E)-2-[4-(trifluoromethyl)phenyl]ethenyl}pyridine(627510-87-6)

Safety Data

• Hazardous Substances Data: 627510-87-6(Hazardous Substances Data)

Upstream product

• 455-19-6 4-Trifluoromethylbenzaldehyde 
• 5832-44-0 3-nitro-4-methylpyridine 

Downstream Products

• 627510-99-0 2-(4-trifluoromethylphenyl)-1H-pyrrolo[2,3-c]pyridin-1-ol 
• 627511-04-0 2-(4-trifluoromethylphenyl)-1H-pyrrolo[2,3-c]pyridine 
• 627510-93-4 N-(4-{(E)-2-[4-(trifluoromethyl)phenyl]ethenyl}pyridin-3-yl)hydroxylamine 

Relevant articles and documents

Synthesis of 2-aryl-1-hydroxyazaindoles and 2-arylazaindoles via oxidation of o-hydroxyaminostyrylpyridines

2-Aryl-1-hydroxyazaindoles (pyrrolopyridin-1-ols) are prepared via an oxidation/cyclization of o-hydroxyaminostyrylpyridines with DDQ. Reduction of the N-OH bond affords the corresponding 2-arylazaindoles (1H-pyrrolopyridines). The scope of the cyclization is explored via (i) the condensation of 4-methyl-3-nitropyridine with various aryl aldehydes to afford 2-aryl substituted 6-azaindoles and, (ii) the synthesis of 2-phenyl-4-, 5- and 7-azaindoles.