627532-13-2Relevant academic research and scientific papers
Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based HTS assay. Part 5: Modifications of the 2- and 3-positions
Kemnitzer, William,Jiang, Songchun,Wang, Yan,Kasibhatla, Shailaja,Crogan-Grundy, Candace,Bubenik, Monica,Labrecque, Denis,Denis, Real,Lamothe, Serge,Attardo, Giorgio,Gourdeau, Henriette,Tseng, Ben,Drewe, John,Cai, Sui Xiong
, p. 603 - 607 (2008/09/17)
As a continuation of our efforts to discover and develop apoptosis inducing 4-aryl-4H-chromenes as novel anticancer agents, we explored modifications at the 2- and 3-positions. It was found that replacement of the 3-cyano group by an ester, including meth
