62761-45-9Relevant academic research and scientific papers
Zinc Chloride Mediated Synthesis of 3H-Oxazol-2-one and Pyrrolo-oxazin-1-one from Ynamide
Habert, Lo?c,Sallio, Romain,Durandetti, Muriel,Gosmini, Corinne,Gillaizeau, Isabelle
supporting information, p. 5175 - 5179 (2019/09/06)
A simple zinc chloride mediated cyclization of ynamidyl N-carbamates or 2-ynamidyl-(hetero)arylcarboxylates is achieved under mild reaction conditions, leading to the synthesis of useful heterocyclic scaffolds, 3H-oxazol-2-ones and pyrrolo-oxazin-1-ones, with good yields.
Synthesis of functionalized oxazolones by a sequence of Cu(ll)- And Au(l)-catalyzed transformations
Istrate, Florin M.,Buzas, Andrea K.,Jurberg, Igor Dias,Odabachian, Yann,Gagosz, Fabien
supporting information; experimental part, p. 925 - 928 (2009/04/07)
A study concerning a two-step sequence leading to the formation of diversely 1,5-disubstituted oxazolones is described. The mild conditions employed allow the efficient and rapid synthesis of a variety of such compounds via an initial Cu(II)-catalyzed coupling of a bromoalkyne with a secondary tert-butyloxycarbamate followed by a Au(l)-catalyzed cycloisomerization of the N-alkynyl tert-butyloxycarbamates thus obtained.
