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1-[2-(4-methylphenyl)-2-oxoethyl]pyridinium is a chemical compound characterized by a pyridinium ring and a side chain that includes a 4-methylphenyl group and a 2-oxoethyl group. It is recognized for its potential as a corrosion inhibitor and its antimicrobial and antifungal properties. 1-[2-(4-methylphenyl)-2-oxoethyl]pyridinium is also of interest in pharmaceutical research and organic synthesis, serving as a key intermediate in the preparation of various compounds. Moreover, it has been studied for its potential therapeutic applications in treating diseases like cancer and Alzheimer's, attributed to its ability to modulate specific biological pathways. However, further research is necessary to fully comprehend its biological effects and potential applications.

6277-45-8

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6277-45-8 Usage

Uses

Used in Organic Synthesis:
1-[2-(4-methylphenyl)-2-oxoethyl]pyridinium is used as a key intermediate in the synthesis of various organic compounds, contributing to the development of new chemical entities with diverse applications.
Used in Pharmaceutical Research:
In pharmaceutical research, 1-[2-(4-methylphenyl)-2-oxoethyl]pyridinium is utilized as a crucial component in the preparation of pharmaceuticals, potentially leading to the discovery of novel drugs with improved therapeutic effects.
Used as a Corrosion Inhibitor:
1-[2-(4-methylphenyl)-2-oxoethyl]pyridinium is employed as a corrosion inhibitor, helping to protect materials from degradation and extending their service life in various industrial applications.
Used for Antimicrobial and Anti-Fungal Applications:
1-[2-(4-methylphenyl)-2-oxoethyl]pyridinium is used for its antimicrobial and antifungal properties, making it a potential candidate for use in sanitizing products and treatments to combat microbial infections.
Used in Disease Treatment Research:
In the field of disease treatment research, 1-[2-(4-methylphenyl)-2-oxoethyl]pyridinium is studied for its potential use in treating various diseases, such as cancer and Alzheimer's, due to its ability to modulate certain biological pathways. Further research is required to explore its full therapeutic potential.

Check Digit Verification of cas no

The CAS Registry Mumber 6277-45-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,7 and 7 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6277-45:
(6*6)+(5*2)+(4*7)+(3*7)+(2*4)+(1*5)=108
108 % 10 = 8
So 6277-45-8 is a valid CAS Registry Number.

6277-45-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(4-methylphenyl)-2-pyridin-1-ium-1-ylethanone,iodide

1.2 Other means of identification

Product number -
Other names HMS2853L10

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6277-45-8 SDS

6277-45-8Relevant academic research and scientific papers

Cyclization of Active Methylene Isocyanides with α-Oxodithioesters Induced by Base: An Expedient Synthesis of 4-Methylthio/Ethoxycarbonyl-5-acylthiazoles

Anil, Seegehalli M.,Kiran, Kuppalli R.,Rajeev, Narasimhamurthy,Rangappa, Kanchugarakoppal S.,Sadashiva, Maralinganadoddi P.,Swaroop, Toreshettahally R.

, p. 1444 - 1450 (2020/04/27)

Cyclization of tosylmethyl isocyanide with α-oxodithioesters in the presence of KOH is reported for the synthesis of 4-methylthio-5-acylthiazoles. Similarly, ethyl isocyanoacetate underwent cyclization with α-oxodithioesters to form 4-ethoxycarbonyl-5-acy

NANOSCALE METAL-ORGANIC LAYERS AND METAL-ORGANIC NANOPLATES FOR X-RAY INDUCED PHOTODYNAMIC THERAPY, RADIOTHERAPY, RODIODYNAMIC THERAPY, CHEMOTHERAPY, IMMUNOTHERAPY, AND ANY COMBINATION THEREOF

-

Page/Page column 73, (2019/02/17)

Metal-organic layers (MOLs) and metal-organic nanoplates (MOPs) comprising photosensitizers are described. The MOLs and MOPs can also include moieties capable of absorbing X-rays or other ionizing irradiation energy and/or scintillation. Optionally, the p

Acid-Catalyzed Condensation of o-Phenylenediammines and o-Aminophenols with α-Oxodithioesters: A Divergent and Regio? selective Synthesis of 2-Methylthio-3-Aryl/Heteroarylquinoxalines and 2-Acylbenzoxazoles

Anil, Seegehally M,Kiran, Kuppalli R,Rangappa, Kanchugarakoppal S,Sadashiva, Maralinganadoddi P,Shruthi, Jeegundipattana B,Sukrutha, Kodipura P,Swaroop, Toreshettahally R

, p. 4205 - 4214 (2019/11/14)

o-Phenylenediammines and o-Aminophenols were reacted with α-oxodithioesters in a highly regioselective fashion to give 2-methylthio-3-Aryl/heteroarylquinoxalines and 2-Acylbenzoxazoles in 55-94percent and 45-86percent, respectively, in the presence of p-T

Nanoscale Metal–Organic Layers for Deeply Penetrating X-ray-Induced Photodynamic Therapy

Lan, Guangxu,Ni, Kaiyuan,Xu, Ruoyu,Lu, Kuangda,Lin, Zekai,Chan, Christina,Lin, Wenbin

supporting information, p. 12102 - 12106 (2017/09/06)

We report the rational design of metal–organic layers (MOLs) that are built from [Hf6O4(OH)4(HCO2)6] secondary building units (SBUs) and Ir[bpy(ppy)2]+- or [Ru(bpy)3]

Coupling of azomethine ylides with nitrilium derivatives of closo-decaborate clusters: A synthetic and theoretical study

Mindich, Aleksey L.,Bokach, Nadezhda A.,Kuznetsov, Maxim L.,Haukka, Matti,Zhdanov, Andrey P.,Zhizhin, Konstantin Yu.,Miltsov, Serguei A.,Kuznetsov, Nikolay T.,Kukushkin, Vadim Yu.

, p. 1075 - 1086 (2013/03/13)

The azomethine ylides p-R3C5H4N+CHCOC 6H4R2-p (3a: R3=H, R2=H, X=Br; 3b: R3=H, R2=Me, X=I; 3c: R3=H, R2=OMe, X=I; 3d: R3=H, R2=F, X=I; 3e: R3=Me, R2=Me, X=Br) react with the nitrile functio

2-Thienyl-4-furyl-6-aryl pyridine derivatives: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study

Thapa, Pritam,Karki, Radha,Thapa, Uttam,Jahng, Yurngdong,Jung, Mi-Ja,Nam, Jung Min,Na, Younghwa,Kwon, Youngjoo,Lee, Eung-Seok

experimental part, p. 377 - 386 (2010/04/02)

Designed and synthesized 60 2-thienyl-4-furyl-6-aryl pyridine derivatives were evaluated for their topoisomerase I and II inhibitory activities at 20 μM and 100 μM and cytotoxicity against several human cancer cell lines. Compounds 8, 9, 11-29 showed sign

Synthesis of 2-(thienyl-2-yl or -3-yl)-4-furyl-6-aryl pyridine derivatives and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship

Thapa, Pritam,Karki, Radha,Choi, Hoyoung,Choi, Jae Hun,Yun, Minho,Jeong, Byeong-Seon,Jung, Mi-Ja,Nam, Jung Min,Na, Younghwa,Cho, Won-Jea,Kwon, Youngjoo,Lee, Eung-Seok

experimental part, p. 2245 - 2254 (2010/06/14)

A series of 2-(thienyl-2-yl or -3-yl)-4-furyl-6-aryl pyridine derivatives were designed, synthesized, and evaluated for their topoisomerase I and II inhibition and cytotoxic activity against several human cancer cell lines. Compounds 10-19 showed moderate

SYNTHESIS AND STRUCTURAL STUDY ON Α-SUBSTITUED-1-STYRYLPYRIDINIUM SALTS. REINVESTIGATION OF KROHNKE CONDENSATION

Alvarez-Builla, J.,Novella, J. L.,Galvez, E.,Smith, P.,Florencio, F.,et al.

, p. 699 - 708 (2007/10/02)

Kroehnke condensation of several cycloimmonium salts with p-dimethylaminobenzaldehyde has been studied.X-Ray diffraction, IR and Raman spectra, 1H- and 13C-NMR and UV spectra of the products are discussed, being compared, when necessary, with the starting pyridinium salts.All compounds showed the Z configuration, corresponding to the more stable structure, except one, in which steric factors were predominant.

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