Basic information

Product Name: [(2-methyl-6-oxo-5,6-dihydro-3H-purin-8-yl)sulfanyl]acetic acid
Synonyms:
CAS NO:6278-99-5
Molecular Formula: C₈H₈N₄O₃S
Molecular Weight: 240.2391
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: 439.1°C at 760 mmHg
Flash Point: 219.4°C
Appearance: N/A
Density: 1.86g/cm³
Vapor Pressure: 6.14E-09mmHg at 25°C
Refractive Index: 1.833
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: [(2-methyl-6-oxo-5,6-dihydro-3H-purin-8-yl)sulfanyl]acetic acid(CAS DataBase Reference)
NIST Chemistry Reference: [(2-methyl-6-oxo-5,6-dihydro-3H-purin-8-yl)sulfanyl]acetic acid(6278-99-5)
EPA Substance Registry System: [(2-methyl-6-oxo-5,6-dihydro-3H-purin-8-yl)sulfanyl]acetic acid(6278-99-5)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 6278-99-5(Hazardous Substances Data)

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Usage
SDS
Upstream product
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6278-99-5 Usage

Uses

Used in Oncology:
6-thioguanine is used as an anticancer agent for the treatment of various types of leukemia, including acute myeloid leukemia and acute lymphoblastic leukemia. It is particularly effective in targeting rapidly dividing cancer cells by interfering with their DNA and RNA synthesis, thus inhibiting their growth and spread.
Used in Inflammatory Bowel Disease Treatment:
In the field of gastroenterology, 6-thioguanine is utilized for the treatment of inflammatory bowel disease. Its anti-inflammatory properties help reduce inflammation in the intestines, providing relief from symptoms and promoting intestinal healing.
Used in Pharmaceutical Formulation:
6-thioguanine is commonly administered orally in the form of tablets, allowing for convenient and controlled drug delivery. However, due to its potential side effects, such as bone marrow suppression and liver toxicity, careful monitoring and dosage adjustments are necessary to ensure patient safety and maximize therapeutic outcomes.
Used in Research and Development:
In the pharmaceutical and biotechnology industries, 6-thioguanine serves as a valuable compound for research and development. Its unique mechanism of action and potential applications in cancer treatment and other conditions make it an important subject of study for the development of new drugs and therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 6278-99-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,7 and 8 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 6278-99:
(6*6)+(5*2)+(4*7)+(3*8)+(2*9)+(1*9)=125
125 % 10 = 5
So 6278-99-5 is a valid CAS Registry Number.

6278-99-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	2-[(2-methyl-6-oxo-3,7-dihydropurin-8-yl)sulfanyl]acetic acid

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6278-99-5 SDS

6278-99-5Upstream product

6278-99-5Downstream Products

1494-14-0 (2-methyl-6-oxo-6,7-dihydro-1H-purin-8-ylmercapto)-acetic acid-(4-fluoro-anilide)

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