62796-84-3

Basic information

• Product Name: 1,4,7,10,13,16-hexaoxacyclooctadecane-2,6-dione
• CAS NO: 62796-84-3
• Molecular Formula: C₁₂H₂₀O₈
• Molecular Weight: 292.2824
• Mol File: 62796-84-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 520.8°C at 760 mmHg
• Flash Point: 233.8°C
• Density: 1.13g/cm³
• Vapor Pressure: 6.03E-11mmHg at 25°C
• Refractive Index: 1.418
• CAS DataBase Reference: 1,4,7,10,13,16-hexaoxacyclooctadecane-2,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4,7,10,13,16-hexaoxacyclooctadecane-2,6-dione(62796-84-3)
• EPA Substance Registry System: 1,4,7,10,13,16-hexaoxacyclooctadecane-2,6-dione(62796-84-3)

Safety Data

• Hazardous Substances Data: 62796-84-3(Hazardous Substances Data)

Usage

General Description

1,4,7,10,13,16-hexaoxacyclooctadecane-2,6-dione, also known as calix[6]arene, is a chemical compound with the formula C28H24O12. It is a macrocyclic molecule that consists of six para-substituted phenolic units connected by methylene bridges. Calix[6]arene has a wide range of potential applications, including as a host molecule for the encapsulation and selective binding of guest molecules, and as a building block for the construction of functional materials. Its unique structure and properties make it a promising candidate for use in various fields, such as supramolecular chemistry, drug delivery, and molecular recognition. Additionally, calix[6]arene has attracted significant interest in the development of new sensors, catalysts, and materials for biomedical and environmental applications.

Upstream product

• 110-99-6 2,2'-oxybis-acetic acid 
• 112-60-7 Tetraethylene glycol 
• 21062-20-4 diglycolyl chloride 
• 7040-23-5 dimethyl diglycolate 

Downstream Products

• 17455-13-9 18-crown-6 ether 

Relevant articles and documents

Condensation of Diglycolic Acid Dichloride with Polyglycols. 5. An Improved Synthesis of Cyclic Polyether-Esters by Cyclization

An improved synthesis of oligocyclic (ether-ester)s by cyclization condensation of polyglycols with diglycolic acid dichloride in benzene/pyridine or dioxane/pyridine is reported. Keywords: Macrocyclic oligo(ether-ester)s

The Preparation of Macrocyclic Polyether-Diester Compounds by Transesterification Including The Preparation of Two New Nitrogen Containing Diester-Crown Compounds

Macrocyclic polyether-diester compounds have been prepared by reacting oligoethylene glycols with the appropriate dimethyl esters in the presence of catalytic amounts of alkali metal methoxides.The methanol by-product was removed by molecular sieves.Product yields were improved for the preparation of all macrocyclic compounds except a compound containing a furan subcyclic group (4).Six new macrocyclic diester compounds (7-12) could only be prepared using the base catalyzed transesterification process since the acid chloride synthetic method failed or the acid chloride could not be made.The formation of compounds 5 and 6 from dimethyl 2,6-pyridine dicarboxylate (17) and the triethylene and tetraethylene glycols proceeded by way of half-transesterified intermediates.These intermediates were also observed for the base catalyzed decomposition of 5 and 6 in methanol to form the glycol and the diester 17.