62796-84-3

Usage

Uses

Used in Supramolecular Chemistry:
1,4,7,10,13,16-hexaoxacyclooctadecane-2,6-dione is used as a host molecule for the encapsulation and selective binding of guest molecules, playing a crucial role in supramolecular chemistry.
Used in Drug Delivery:
1,4,7,10,13,16-hexaoxacyclooctadecane-2,6-dione is used as a building block for the construction of functional materials in drug delivery systems, enhancing the efficiency and targeting of therapeutic agents.
Used in Molecular Recognition:
1,4,7,10,13,16-hexaoxacyclooctadecane-2,6-dione is used in molecular recognition processes due to its ability to selectively bind with specific molecules, which is vital for various analytical and diagnostic applications.
Used in Sensor Development:
1,4,7,10,13,16-hexaoxacyclooctadecane-2,6-dione is used as a component in the development of new sensors, capitalizing on its selective binding properties to create responsive and sensitive devices.
Used in Catalyst Design:
1,4,7,10,13,16-hexaoxacyclooctadecane-2,6-dione is utilized in the design of catalysts, potentially improving the efficiency and selectivity of chemical reactions.
Used in Biomedical Applications:
1,4,7,10,13,16-hexaoxacyclooctadecane-2,6-dione is used in biomedical applications, such as the development of biocompatible materials and targeted drug delivery systems, due to its unique structure and properties.
Used in Environmental Applications:
1,4,7,10,13,16-hexaoxacyclooctadecane-2,6-dione is employed in environmental applications, including the creation of materials for pollution detection and remediation, as well as in the development of eco-friendly processes and products.

Upstream product

• 112-60-7 Tetraethylene glycol 
• 7040-23-5 dimethyl diglycolate 
• 21062-20-4 diglycolyl chloride 
• 110-99-6 2,2'-oxybis-acetic acid 

Downstream Products

• 17455-13-9 18-crown-6 ether 

Relevant academic research and scientific papers

Synthesis of macrocyclic polyether-diester compounds using Al2O3/MeSO3H (AMA) as a new reagent

A new simple and convenient method for the synthesis of macrocyclic polyether-diester compounds containing pyridine and phenyl subcyclic units is developed. Various diacids, are selectively esterified in excellent yields by reaction with oligoethylene glycols in the presence of Al2O3/MeSO3H (AMA) as a new reagent without use of any solvents.

Condensation of Diglycolic Acid Dichloride with Polyglycols. 5. An Improved Synthesis of Cyclic Polyether-Esters by Cyclization

An improved synthesis of oligocyclic (ether-ester)s by cyclization condensation of polyglycols with diglycolic acid dichloride in benzene/pyridine or dioxane/pyridine is reported. Keywords: Macrocyclic oligo(ether-ester)s

The Preparation of Macrocyclic Polyether-Diester Compounds by Transesterification Including The Preparation of Two New Nitrogen Containing Diester-Crown Compounds

Macrocyclic polyether-diester compounds have been prepared by reacting oligoethylene glycols with the appropriate dimethyl esters in the presence of catalytic amounts of alkali metal methoxides.The methanol by-product was removed by molecular sieves.Product yields were improved for the preparation of all macrocyclic compounds except a compound containing a furan subcyclic group (4).Six new macrocyclic diester compounds (7-12) could only be prepared using the base catalyzed transesterification process since the acid chloride synthetic method failed or the acid chloride could not be made.The formation of compounds 5 and 6 from dimethyl 2,6-pyridine dicarboxylate (17) and the triethylene and tetraethylene glycols proceeded by way of half-transesterified intermediates.These intermediates were also observed for the base catalyzed decomposition of 5 and 6 in methanol to form the glycol and the diester 17.

The Reduction of Crown Lactones to Crown Ethers

Crown lactones may be reduced to crown ethers using lithium aluminium hydride.