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2-methyl-9H-xanthen-9-one, also known as Fluorescein, is a fluorescent dye that is widely utilized in biological research and laboratory applications. It is a polycyclic aromatic compound characterized by its bright green-yellow fluorescence, which makes it a valuable tool for visualizing a range of biological processes. 2-methyl-9H-xanthen-9-one's ability to fluoresce under ultraviolet light is particularly useful for studying cell viability, membrane integrity, and pH changes.

6280-45-1

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6280-45-1 Usage

Uses

Used in Biological Research:
2-methyl-9H-xanthen-9-one is used as a fluorescent marker for visualizing biological processes such as cell viability, membrane integrity, and pH changes. Its fluorescence properties allow researchers to track and monitor these processes in real-time, providing valuable insights into cellular functions and behaviors.
Used as a pH Indicator:
Due to its sensitivity to pH changes, 2-methyl-9H-xanthen-9-one is used as a pH indicator in various applications. The shift in its fluorescence properties in response to different pH levels makes it a useful tool for measuring and monitoring pH in solutions.
Used in the Production of Fluorescent Pigments:
2-methyl-9H-xanthen-9-one is utilized in the production of fluorescent pigments for various industries, including cosmetics, textiles, and paints. Its bright fluorescence enhances the visual appeal and durability of these products.
Used in Medical Imaging and Cancer Diagnostics:
2-methyl-9H-xanthen-9-one has been investigated for its potential use in medical imaging and cancer diagnostics. Its ability to selectively target and bind to certain tissues and proteins makes it a promising candidate for enhancing the visualization and detection of cancerous cells, thereby improving diagnostic accuracy and treatment planning.

Check Digit Verification of cas no

The CAS Registry Mumber 6280-45-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,8 and 0 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6280-45:
(6*6)+(5*2)+(4*8)+(3*0)+(2*4)+(1*5)=91
91 % 10 = 1
So 6280-45-1 is a valid CAS Registry Number.

6280-45-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-methylxanthen-9-one

1.2 Other means of identification

Product number -
Other names 2-methyl-xanthen-9-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6280-45-1 SDS

6280-45-1Relevant academic research and scientific papers

Application to photoreactive materials of photochemical generation of superbases with high efficiency based on photodecarboxylation reactions

Arimitsu, Koji,Endo, Ryosuke

, p. 4461 - 4463 (2014/01/06)

A thin film of polystyrene containing 4c was spin-coated on a CaF2 plate and irradiated with 365 nm light. The absorption band arising from the carboxylate of 4c at 1372 cm-1 in the FTIR spectrum decreased after UV irradiation. Radical UV curing materials that are well established in the marketplace have drawbacks because of high volume shrinkage and oxygen inhibition. The anionically cured film showed high transparency and no volume shrinkage, in contrast to a conventional radical UV curing system, which showed large volume shrinkage. This is probably due to relatively low quantum yields for photobase generation and weaker basicity of photo-generated bases, leading to low photosensitivity of photoreactive materials sensitized with photobase generators. Furthermore, many of the photobase generators reported are generally prepared via several synthetic steps.

Gas-phase Reactions of 2-Benzyl- and 2-Benzoyl-phenoxyl Radicals, and of 2-Phenoxybenzyl Radicals: Examples of New Hydrogen-transfer Processes

Cadogan, J. I. G.,Hutchison, H. Susan,McNab, Hamish

, p. 385 - 393 (2007/10/02)

Generation of the 2-benzylphenoxyl radical 23 or the 2-phenoxybenzyl radical 24 by flash vacuum pyrolysis of the ethers 8 or 9, or the oxalate 19, respectively, leads to fluoren-1-ol 22 together with 2-benzylphenol 7 and a low yield of xanthene 21.Pyrolysis of the para-substituted derivatives 11 and 20 gives an analogous distribution of products, including two isomeric methylxanthenes 28 and 29 formed via the spirodienyl 27.The reactions of the corresponding 2-benzoylphenoxyl radicals give information on the mechanism of these processes.Thus the formation of the fluorenones 37 and 43 provides evidence for the hydrogen-abstraction mechanism (Scheme 4) of fluorene formation.Secondly, a detailed study of the ratios of xanthones 41 and 42 under a variety of pyrolysis conditions suggests that such 6-membered-ring products are formed by sigmatropic shifts in the spirodienyl, rather than direct cyclisation of the phenoxyl or benzoyl radicals.

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