6280-55-3

Usage

Uses

Used in Pharmaceutical Industry:
(3-chlorophenyl)(4-hydroxy-3-methylphenyl)methanone is used as an intermediate compound for the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs with potential therapeutic applications.
Used in Agricultural Chemicals:
In the agricultural sector, (3-chlorophenyl)(4-hydroxy-3-methylphenyl)methanone is utilized as a building block for the creation of different agrochemicals. Its properties make it suitable for the formulation of pesticides, herbicides, and other products aimed at enhancing crop protection and yield.
Used in Dye Industry:
(3-chlorophenyl)(4-hydroxy-3-methylphenyl)methanone is also employed in the production of dyes. Its chemical structure contributes to the development of a wide range of colors and hues, making it a valuable asset in the dye manufacturing process.
Used in Research and Development:
Due to its potential biological and pharmacological activities, such as anti-inflammatory and anti-cancer properties, (3-chlorophenyl)(4-hydroxy-3-methylphenyl)methanone is used as a subject of study in research and development. Scientists and researchers explore its properties to understand its full potential and possible applications in medicine and other fields.
Safety Precautions:
It is crucial to handle (3-chlorophenyl)(4-hydroxy-3-methylphenyl)methanone with care, as it may pose health and environmental risks if not properly managed. Appropriate safety measures, including the use of personal protective equipment and adherence to safety protocols, should be taken to minimize any potential hazards associated with this chemical compound.

Upstream product

• 618-46-2 m-Chlorobenzoyl chloride 
• 95-48-7 ortho-cresol 
• 6280-51-9 2-methylphenyl 3-chlorobenzoate 

Downstream Products

• 1150104-91-8 C₂₁H₂₄ClNO₂ 
• 1323950-41-9 2-(2-(4-(3-chlorobenzoyl)-2-methylphenoxy)acetyl)-N-(2-methylphenyl)hydrazinecarbothioamide 
• 1323950-42-0 2-(2-(4-(3-chlorobenzoyl)-2-methylphenoxy)acetyl)-N-(2-methoxyphenyl)hydrazinecarbothioamide 
• 1323950-43-1 N-(2-bromophenyl)-2-(2-(4-(3-chlorobenzoyl)-2-methylphenoxy)acetyl)hydrazinecarbothioamide 
• 1323950-44-2 2-(2-(4-(3-chlorobenzoyl)-2-methylphenoxy)acetyl)-N-(2-chlorophenyl)hydrazinecarbothioamide 
• 1323950-45-3 2-(2-(4-(3-chlorobenzoyl)-2-methylphenoxy)acetyl)-N-(2-ethylphenyl)hydrazinecarbothioamide 
• 1323950-51-1 (3-chlorophenyl)(3-methyl-4-((5-((2-methylphenyl)amino)-1,3,4-oxadiazol-2-yl)methoxy) phenyl) methanone 
• 1323950-52-2 (3-chlorophenyl)(4-((5-((2-methoxyphenyl)amino)-1,3,4-oxadiazol-2-yl)methoxy)-3-methylphenyl) methanone 
• 1323950-53-3 (4-((5-((2-bromophenyl)amino)-1,3,4-oxadiazol-2-yl)methoxy)-3-methylphenyl)(3-chlorophenyl) methanone 
• 1323950-54-4 (3-chlorophenyl)(4-((5-((2-chlorophenyl)amino)-1,3,4-oxadiazol-2-yl)methoxy)-3-methylphenyl) methanone 
• 1323950-55-5 (3-chlorophenyl)(4-((5-((2-ethylphenyl)amino)-1,3,4-oxadiazol-2-yl)methoxy)-3-methylphenyl)methanone 
• 667891-41-0 ethyl 2-(4-(3-chlorobenzoyl)-2-methylphenoxy)acetate 
• 670221-36-0 2-(4-(3-chlorobenzoyl)-2-methylphenoxy)acetohydrazide 
• 6279-20-5 4-(3-chloro-benzyl)-2-methyl-phenol 

Relevant academic research and scientific papers

TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF

Disclosed is a tetrazolinone compound having a high pest control effect and represented by the formula (1): wherein R1, R2, R3, and R11 each represent a halogen atom, a C1-C6 alkyl group, or the like; R4 and R5 each represent a hydrogen atom, a halogen atom, a C1-C3 alkyl group, or the like; R6 represents a C1-C3 alkyl group which may have a halogen atom(s) or the like; R7, R8, and R9 each represent a hydrogen atom, a halogen atom, or the like; R10 represents a C1-C3 alkyl group or the like; R12 represents a C1-C6 alkyl group, a C3-C6 cycloalkyl group, or the like, and R13 represents a C1-C6 alkyl group, a C2-C6 alkenyl group, or the like.

Design, synthesis, and anticancer properties of novel benzophenone- conjugated coumarin analogs

In the current scenario, development of anticancer drugs with specific targets is of prime importance in modern chemical biology. Observing the importance of benzophenone and coumarin nucleus, it would be worthwhile to design and synthesize novel benzophenone derivatives (8a-o) bearing the coumarin nucleus. Further, they were screened for prospective anticancer activities in vitro against the Michigan Cancer Foundation-7 (MCF-7) and Ehrlich's ascites tumor (EAT) cell lines and their biomarkers, followed by in silico studies regarding phosphoinositide 3-kinase (PI3K) and caspase by molecular docking. Benzophenones have been reported as potential drugs targeting tumor angiogenesis; thus, the formation of neovessels in an in vivo model system like CAM, which is angiogenesis dependent, was observed in the presence of compounds 8a-o. The above findings would help in understanding their putative potential as therapeutic agents for cancer patients. Coumarin-integrated benzophenone conjugates (8a-o) were designed, synthesized, and screened for prospective anticancer activities in vitro against the MCF-7 and EAT cell lines. Molecular docking studies with regard to phosphoinositide 3-kinase and caspase were performed. In addition, neovessel formation was observed in an in vivo model system.

Benzophenone-N-ethyl piperidine ether analogues-Synthesis and efficacy as anti-inflammatory agent

A sequence of substituted benzophenone-N-ethyl piperidine ether analogues has been synthesized and evaluated as orally active anti-inflammatory agents with reduced side effects. The anti-inflammatory and ulcerogenic activities of the compounds were compared with naproxen, indomethacin, and phenylbutazone. These analogues showed an interesting anti-inflammatory activity in carrageenan-induced foot pad edema assay. In the air-pouch test, some of the analogues reduced the total number of leukocytes of the exudate, which indicates inhibition of prostaglandin production. Side effects of the compounds were examined on gastric mucosa, in the liver and stomach. None of the compounds illustrated significant side effects compared with standard drugs like indomethacin and naproxen.

Synthesis of 5-(4′-aroyl)-aryloxy methyl-4H-(1,2,4)-triazolin-3-thiol and their biological activity

5-(4′-aroyl)-aryloxy methyl-4H-1,2, 4)-triazolin-3-thiols were synthesized by using substituted phenyl benzoates as the starting material. Phenyl benzoates on Fries rearrangement gave p-hydroxy benzophenones which on treatment with ethyl bromoacetate in presence of anhydrous potassium carbonate and dry acetone gave corresponding benzoyl phenyloxy esters in excellent yield. Esters were refluxed with thiosemicarbazide in presence of acetic anhydride gave cyclized title compounds. Supports for the structures of the synthesized compounds have been provided by their elemental analysis and spectral data. The newly synthesized compounds were screened for antibacterial and antifungal activities.