62827-46-7

Basic information

• Product Name: Benzamide, 2-bromo-4,6-dimethoxy-
• CAS NO: 62827-46-7
• Molecular Formula: C9H10BrNO3
• Molecular Weight: 260.087
• Mol File: 62827-46-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzamide, 2-bromo-4,6-dimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 2-bromo-4,6-dimethoxy-(62827-46-7)
• EPA Substance Registry System: Benzamide, 2-bromo-4,6-dimethoxy-(62827-46-7)

Safety Data

• Hazardous Substances Data: 62827-46-7(Hazardous Substances Data)

Upstream product

• 62827-49-0 2-bromo-4,6-dimethoxybenzoic acid 
• 81574-69-8 2-bromo-4,6-dimethoxybenzaldehyde 
• 20469-65-2 1-bromo-3,5-dimethoxybenzene 

Downstream Products

• 1044870-39-4 2-(4-(2-hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethoxy-3,4-dihydroquinazoline-4-one 

Relevant articles and documents

Preparation method for Apabetalone

The invention relates to a preparation method for Apabetalone, and particularly discloses a synthesis method for Apabetalone. The preparation method comprises the following steps: (1) a first intermediate, i.e., 2-bromo-4,6-dimethoxy benzamide, is prepared; (2) a second intermediate, i.e., 4-{2-[(t-butyldimethylsilicon)oxy]ethyoxyl}-3,5-dimethyl benzaldehyde, is prepared; (3) the first intermediate and the second intermediate are sealed under the conditions of cuprous bromide, cesium carbonate, L-proline and ammonia hydroxide to react, so that Apabetalone is obtained. The preparation method disclosed by the invention is simple, and yield is high.