62829-75-8Relevant academic research and scientific papers
1-phenothiazinyl-3-aryl-4-acetyl-1, 5-hexanedione and preparation method thereof
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Paragraph 0083-0086, (2017/10/07)
The invention provides 1-phenothiazinyl-3-aryl-4-acetyl-1, 5-hexanedione and a preparation method thereof. The 1-phenothiazinyl-3-aryl-4-acetyl-1, 5-hexanedione adopts the structural formula as follows: FORMULA. The preparation method comprises the following steps: adding 1-phenothiazinyl-3-aryl-propenone, a catalyst and acetylacetone into a dry mortar, grinding, reacting, performing TLC tracking detection until a reaction is complete, then washing by using water, performing suction filtration, and drying a filter cake to obtain the 1-phenothiazinyl-3-aryl-4-acetyl-1, 5-hexanedione. The preparation method has the advantages of a short reaction time, no solvent, environment friendliness, economy, simple operation, mild reaction conditions, simple post-treatment and high yield. The prepared 1-phenothiazinyl-3-aryl-4-acetyl-1, 5-hexanedione includes a series of brand-new phenothiazinyl-containing ketone derivatives, has sterilizing and bacteriostatic effects and the like, and has a very good application prospect in the antibacterial and anti-virus fields and the like.
