628292-86-4

Upstream product

• 108-24-7 acetic anhydride 
• 26922-94-1 (1S,3R,4R,5S,8R)-8-benzyloxy-3,4-isopropylidenedioxy-2,6-dioxabicyclo[3.3.0]octane 

Downstream Products

• 475558-28-2 1-(2'-O-acetyl-3',6'-anhydro-5'-O-benzyl-β-D-glucofuranosyl)-thymine 
• 628292-87-5 1-(2'-O-acetyl-3',6'-anhydro-5'-O-benzyl-α-D-glucofuranosyl)thymine 
• 628292-88-6 1-(3',6'-anhydro-5'-O-benzyl-α-D-glucofuranosyl)thymine 
• 259746-16-2 1,2-di-O-acetyl-3,6-anhydro-5-O-benzyl-α,β-D-glucofuranose 

Relevant academic research and scientific papers

Controlled acetolysis of 3,6-anhydro-5-o-benzyl-1,2-o-isopropylidene-α-D-glucofuranose: Synthesis of 1-(3′,6′-anhydro-α-D-glucofuranosyl)thymine

Controlled acetolysis of 1,2-O-isopropylideneglucofuranose derivative 1 in Ac2O:AcOH:H2SO4 at 0°C is reported to isolate 2-acetoxy dimethylmethylenoxy glucofuranose derivative 2 in quantitative yield. Utility of 2 for the synthesis of alpha linked nucleoside 5a is demonstrated.