628305-82-8

Upstream product

• 109-01-3 1-methyl-piperazine 
• 628325-55-3 (2-methyl-[1,3]dioxan-2-yl)benzaldehyde 
• 24257-93-0 2-acetylbenzaldehyde 

Downstream Products

• 1204230-94-3 C₂₇H₃₃N₃O₃ 
• 1123622-42-3 tert-butyl (E)-3-(3-{(E)-3-[2-(4-methyl-piperazin-1-yl-methyl)-phenyl]-3-oxo-propenyl}-phenyl) acrylate 
• 1123622-52-5 tert-butyl (E)-3-(6-{(E)-3-[2-(4-methyl-piperazin-1-yl-methyl)-phenyl]-3-oxo-propenyl}-pyridin-2-yl)-acrylate 
• 952391-10-5 C₂₄H₂₆N₂O₃ 

Relevant academic research and scientific papers

Synthesis and biological evaluation of N-hydroxyphenylacrylamides and N-hydroxypyridin-2-ylacrylamides as novel histone deacetylase inhibitors

The histone deacetylases (HDACs) are able to regulate gene expression, and histone deacetylase inhibitors (HDACi) emerged as a new class of agents in the treatment of cancer as well as other human disorders such as neurodegenerative diseases. In the prese

A new class of histone deacetylase inhibitors

This invention is related to new histone deacetylase inhibitors according to the general formula (I) wherein: Q is a bond, CH2, NR5 or oxygen, X is CH or nitrogen, Y is a bond, CH2, oxygen or NR6, Z is CH or nit

A NEW CLASS OF HISTONE DEACETYLASE INHIBITORS

New histone deacetylase inhibitors according to the general formula (I) wherein: Q is a bond, CH2, CH-NR3R4, NR5 or oxygen, X is CH or nitrogen, Y is a bond, CH2, oxygen or NR6, Z is CH or

AMINOALKOXY-FUNCTIONAL CHALCONES

The invention provides novel alkoxyaminochalcone derivatives and analogues thereof. Use of the compounds, or compositions comprising them, as pharmaceutically active agents, in particular against bacterial and parasitic infections, is also disclosed. The

AMINO-FUNCTIONAL CHALCONES

The invention provides novel amino-functionalised chalcone derivatives and analogues thereof. Use of the compounds, or compositions comprising them, as pharmaceutically active agents, in particular against bacterial and parasitic infections, is also discl