62838-11-3

Basic information

• Product Name: 3-(2'-anilinoethyl)-quinazolin-4-one
• CAS NO: 62838-11-3
• Molecular Weight: 265.315
• Mol File: 62838-11-3.mol

Chemical Properties

• CAS DataBase Reference: 3-(2'-anilinoethyl)-quinazolin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2'-anilinoethyl)-quinazolin-4-one(62838-11-3)
• EPA Substance Registry System: 3-(2'-anilinoethyl)-quinazolin-4-one(62838-11-3)

Safety Data

• Hazardous Substances Data: 62838-11-3(Hazardous Substances Data)

Upstream product

• 90772-23-9 N³-(2-bromoethyl)quinazolin-4-one 
• 62-53-3 aniline 

Relevant articles and documents

THE REACTION OF QUINAZOLIN-4-ONES WITH ORGANO-METALLIC AGENTS- A PERSISTENT PREFERENCE FOR RING RUPTURE OVER CYCLIZATION

A range of 3-substituted quinazolin-4-ones whose conjugate bases can undergo intramolecular cyclization to tricyclic systems, have been prepared (Scheme 2).The reaction of these with a variety of organolithium agents gave products arising from reagent addition to the quinazolin-4-one 1,2 bond, although experimental results tended to demonstrate that the desired conjugate bases existed in equilibrium with the tricyclic systems.The acetyl salt of 1a with NaH gave product 3c from ring fragmentation.The imidazoquinazoline 8, the parent of which is markedly antihypotensive, resulted from endeavours to prepare a prototype of the desired tricyclic system by an alternative route.Most compounds studied have more than one site for reactivity against the reagents used.The experimental results clearly highlight an overwhelming preference for addition to quinazolin-4-one 1,2 bond.