628687-63-8Relevant academic research and scientific papers
Design, syntheses, and biological evaluations of squamostolide and its related analogs
Lee, Cheng-Lin,Lin, Chi-Fong,Lin, Wan-Ru,Wang, Kun-Sheng,Chang, Ya-Her,Lin, Shinne-Ren,Wu, Yang-Chang,Wu, Ming-Jung
, p. 5864 - 5872 (2007/10/03)
Squamostolide and its related analogs were designed and synthesized for biological evaluation. All these compounds were tested for growth inhibition activities against human tumor cell lines, in which one of the compounds showed the most potent cytotoxici
Synthesis of (15S,16S,21R)-4-deoxyrollicosin analog
Lee, Jeng-Lin,Lin, Chi-Fong,Hsieh, Ling-Yu,Lin, Wan-Ru,Chiu, Huey-Fen,Wu, Yang-Chang,Wang, Kun-Sheng,Wu, Ming-Jung
, p. 7833 - 7835 (2007/10/03)
Synthesis of 4-deoxy rollicosin analog 2 was completed in nine steps, which was based on palladium-catalyzed coupling of two building blocks 3 and 4. Lactone 3 was synthesized from 5-hexyn-1-ol, and vinyl iodide 4 was accessed from L-glutamate and 1-hexyne.
