628703-61-7

Usage

Uses

Used in Organic Synthesis:
5-[(Aminooxy)Methyl]-2-(1H-pyrazol-1-yl)pyridine is used as a building block for the construction of various heterocyclic compounds, contributing to the development of novel organic molecules with potential applications in various fields.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 5-[(Aminooxy)Methyl]-2-(1H-pyrazol-1-yl)pyridine is utilized as a drug candidate for the treatment of certain diseases. Its unique structure and functional groups make it a promising candidate for the development of new therapeutic agents.
Used in Bioconjugation and Chemical Biology:
The aminooxy group present in the molecule of 5-[(Aminooxy)Methyl]-2-(1H-pyrazol-1-yl)pyridine makes it a valuable tool for bioconjugation and related applications in chemical biology. It can be used to modify biomolecules, such as proteins or nucleic acids, enabling the development of new bioconjugates with specific functions and properties.

Upstream product

• 70258-18-3 2-chloro-5-(chloromethyl)pyridine 
• 307929-00-6 O-(2-chloropyridin-5-yl)methyl acetone oxime 
• 896100-11-1 2-(1-pyrazolyl)-5-pyridyl-N-methoxysuccinimide 
• 896100-09-7 O-(2-(pyrazol-1-yl)pyridin-5-yl)methyl acetone oxime 
• 896100-06-4 O-[2-(pyrazole-1-yl)pyridine-5-yl]methyl 2-butanone oxime 
• 748796-40-9 2-(6-pyrazol-1-yl-pyridin-3-ylmethoxy)-isoindole-1,3-dione 

Relevant academic research and scientific papers

A practical synthetic method of O -(2-(Pyrazol-1-yl)pyridin-5-yl) methylhydroxylamine as a component of modithromycin

A practical synthesis of O-(2-(pyrazol-1-yl)pyridin-5-yl) methylhydroxylamine was achieved from the inexpensive raw materials, 2-chloro-5-chloromethylpyridine, pyrazole, and acetone oxime, using common reagents such as aq NaOH and sulfuric acid.

Processes for the preparation of O-(6-pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine

The present invention relates generally to novel methods for the synthesis of O-(6-pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine which is an essential reagent in the synthesis of one of the bridged erythromycin derivatives and their respective pharmaceutically acceptable salts in PCT Application WO 03/097659 A1. In particular, the present invention relates to processes and intermediates for the preparation of a compound of formula (Ia):

2-(PYRAZOL-1-YL)PYRIDINE DERIVATIVE

A compound having the formula (1): can be produced with efficiency by using a compound represented by the formula (2): wherein R represents a protected hydroxyl group or a group represented by the formula (3): where R1 represents an alkyl group or an aralkyl group which may be substituted; and R2 represents an alkyl.

PROCESS FOR THE PREPARATION OF T-11 BICYCLIC ERYTHROMYCIN DERIVATIVES

The present invention relates to processes and intermediates for the preparation of 6-11 bicyclic erythromycin derivatives. In particular, the presen tinvention relates to processes and intermediates for the preparation of a compound of formula (IX-c).

Processes for the preparation of 6-11 bicyclic erythromycin derivatives

The present invention relates to processes and intermediates for the preparation of 6-11 bicyclic erythromycin derivatives. In particular, the present invention relates to processes and intermediates for the preparation of a compound of formula (IX-c):