62924-59-8 Usage
General Description
2-Chloro-N-ethyl-6-fluorobenzenemethanamine is a chemical compound with the molecular formula C10H12ClFN. It is an organic compound with a chloro substituent, an ethyl group, and a fluorine atom attached to a benzene ring. 2-Chloro-N-ethyl-6-fluorobenzenemethanamine is commonly used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. It has also been studied for its potential applications in the field of medicinal chemistry. The specific properties and uses of this chemical compound make it an important building block for the development of new pharmaceuticals and other bioactive molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 62924-59-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,9,2 and 4 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 62924-59:
(7*6)+(6*2)+(5*9)+(4*2)+(3*4)+(2*5)+(1*9)=138
138 % 10 = 8
So 62924-59-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H11ClFN/c1-2-12-6-7-8(10)4-3-5-9(7)11/h3-5,12H,2,6H2,1H3
62924-59-8Relevant articles and documents
Pyrano-[2,3b]-pyridines as potassium channel antagonists
Finlay, Heather J.,Lloyd, John,Nyman, Michael,Conder, Mary Lee,West, Tonya,Levesque, Paul,Atwal, Karnail
, p. 2714 - 2718 (2008/12/21)
The design and synthesis of a series of highly functionalized pyrano-[2,3b]-pyridines is described. These compounds were assayed for their ability to block the IKur channel encoded by the gene hKV1.5 in patch-clamped L-929 cells. Six of the compounds in this series showed sub-micromolar activity, the most potent being 4-(4-ethyl-benzenesulfonylamino)-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3b]-pyridine-6-carboxylic acid ethyl-phenyl-amide with an IC50 of 378 nM.
