62935-73-3

Basic information

• Product Name: METHYL 7-METHOXYCOUMARIN-4-ACETATE
• Synonyms: METHYL 7-METHOXYCOUMARIN-4-ACETATE;Methyl (7-methoxy-2-oxo-2H-chromen-4-yl)acetate;2-(2-keto-7-methoxy-chromen-4-yl)acetic acid methyl ester;2-(7-methoxy-2-oxo-4-chromenyl)acetic acid methyl ester;methyl 2-(7-methoxy-2-oxo-chromen-4-yl)acetate;methyl 2-(7-methoxy-2-oxochromen-4-yl)acetate;methyl 2-(7-methoxy-2-oxo-chromen-4-yl)ethanoate
• CAS NO: 62935-73-3
• Molecular Formula: C13H12O5
• Molecular Weight: 248.23
• Mol File: 62935-73-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: METHYL 7-METHOXYCOUMARIN-4-ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 7-METHOXYCOUMARIN-4-ACETATE(62935-73-3)
• EPA Substance Registry System: METHYL 7-METHOXYCOUMARIN-4-ACETATE(62935-73-3)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 62935-73-3(Hazardous Substances Data)

Upstream product

• 6950-82-9 2-(7-hydroxy-2-oxochromen-4-yl)acetic acid 
• 77-78-1 dimethyl sulfate 
• 62935-72-2 2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetic acid 
• 150-19-6 O-methylresorcine 
• 1830-54-2 3-oxopentanedioic acid dimethyl ester 
• 108-46-3 recorcinol 
• 15991-13-6 7-hydroxycoumarin-4-acetic acid methyl ester 

Downstream Products

• 74083-58-2 (7-hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid ethyl ester 
• 62935-72-2 2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetic acid 

Relevant articles and documents

Readily functionalizable phosphonium-tagged fluorescent coumarins for enhanced detection of conjugates by mass spectrometry

Fluorescent coumarins are an important class of small-molecule organic fluorophores ubiquitous in different well-established and emerging fields of research including, among others, biochemistry and chemical biology. The present work aims at covering the poor detectability of coumarin-based conjugates by mass spectrometry while keeping important photophysical properties of the coumarin core. In this context, the synthesis of readily functionalizable phosphonium-tagged coumarin derivatives enabling a dual mass-tag and fluorescence labelling of analytes or (bio)molecules of interest through a single-step protocol, is reported. The utility of these coumarins is illustrated through the preparation of fluorogenic substrates that facilitated identification of the peptide fragment released by specific proteolytic cleavages.