62940-83-4Relevant academic research and scientific papers
Bio-Catalytic Bis-Michael Reaction for Generating Cyclohexanones with a Quaternary Carbon Center Using Glucoamylase
Zhang, Yong,Li, Rui,He, Yan-Hong,Guan, Zhi
, p. 633 - 639 (2017/03/08)
Abstract: Bio-catalytic bis-Michael reaction for the construction of quaternary carbon centers is reported. Glucoamylase from Aspergillus niger (AnGA) was used as a sustainable and eco-friendly catalyst. Various highly substituted trans-cyclohexanones wit
Quinine-catalysed double Michael addition of malononitrile to 1,5-disubstituted pentadien-3-ones: A stereoselective route to cyclohexanones
De Fusco, Claudia,Lattanzi, Alessandra
supporting information; experimental part, p. 3728 - 3731 (2011/09/16)
The stereoselective synthesis of 4-oxo-2,6-diaryl-cyclohexane-1,1- dicarbonitriles has been developed through double Michael addition of malononitrile to 1,5-disubstituted pentadien-3-ones catalysed by quinine. This simple cascade process affords cyclohex
Asymmetric organocatalytic double-conjugate addition of malononitrile to dienones: Efficient synthesis of optically active cyclohexanones
Li, Xue-Ming,Wang, Bo,Zhang, Jun-Min,Yan, Ming
supporting information; experimental part, p. 374 - 377 (2011/04/15)
9-Amino-9-deoxyepiquinine efficiently catalyzed the double-conjugate addition of malononitrile to dienones. A number of 1,1,2,6-tetrasubstituted cyclohexanones were prepared in good yields, diastereoselectivities, and excellent enantioselectivities.
