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Bicyclo[2.2.1]heptane-2,3-dicarbonitrile is a cyclic organic compound with the molecular formula C9H10N2. It features a bicyclic structure with two carbon-carbon double bonds and two nitrile groups (C≡N). bicyclo[2.2.1]heptane-2,3-dicarbonitrile is known for its unique shape, which consists of two fused six-membered rings, and it is a valuable building block in organic synthesis. It can be used to synthesize various pharmaceuticals, agrochemicals, and other specialty chemicals due to its reactive nitrile groups and rigid bicyclic framework. The compound's properties, such as its reactivity and stability, make it a versatile intermediate in the synthesis of complex molecules.

6295-85-8

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6295-85-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6295-85-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,9 and 5 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6295-85:
(6*6)+(5*2)+(4*9)+(3*5)+(2*8)+(1*5)=118
118 % 10 = 8
So 6295-85-8 is a valid CAS Registry Number.

6295-85-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name bicyclo[2.2.1]heptane-2,3-dicarbonitrile

1.2 Other means of identification

Product number -
Other names exo,exo-2.3-Dicyano-bicyclo<2.2.1>heptan

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6295-85-8 SDS

6295-85-8Relevant academic research and scientific papers

Synthesis, biophysical studies, and antiproliferative activity of platinum(II) complexes having 1,2-bis(aminomethyl)carbobicyclic ligands

De Mier-Vinué, Jordi,Gay, Marina,Monta?a, ángel M.,Sáez, Rosa-Isabel,Moreno, Virtudes,Kasparkova, Jana,Vrana, Oldrich,Heringova, Pavla,Brabec, Viktor,Boccarelli, Angela,Coluccia, Mauro,Natile, Giovanni

, p. 424 - 431 (2008/09/19)

A selected chemical library of six platinum(II) complexes having 1,2-bis(aminomethyl)carbobicyclic ligands were synthesized after a rational design in order to evaluate their antiproliferative activity and the structure-activity relationships. The cytotoxicity studies were performed using cancer cell lines sensitive (A2780) and resistant (A2780R) to cisplatin. Excellent cytotoxicity was observed for most of complexes, which presented better resistance factors than cisplatin against the A2780R cell line. The interaction of these complexes with DNA, as the target biomolecule, was evaluated by several methods: DNA-platinum binding kinetics, changes in the DNA melting temperature, evaluation of the unwinding angle of supercoiled DNA, evaluation of the interstrand cross-links, and replication mapping. The kinetics of the interaction with glutathione was also investigated to better understand the resistant factors observed for the new complexes.

SYNTHESIS OF anti-SESQUINORBORNENE AND RELATED POLYCYCLIC ALKENES via REDUCTIVE ELIMINATION OF VICINAL DICYANO DERIVATIVES

Lucchi, Ottorino De,Piccolrovazzi, Nicoletta,Licini, Giulia,Modena, Giorgio,Valle, Giovanni

, p. 401 - 408 (2007/10/02)

A methodology for the preparation of both endocyclic unsaturated molecules via reductive elimination of vicinal dicyano derivatives is reported.The method is useful for the preparation of anti-sesquinorbornene and related hitherto unknown molecules starting from the respective vicinal dicyano derivatives which are readily available via Diels-Alder reactions.From a practical point of view, the best decyanation procedure for these substrates is to use finely dispersed sodium in tetrahydrofuran under sonication.The X-ray analysis of anti-1,4,4a,5,8,8a-hexahydro-1,4;5,8-dimethanonaphthalene-4a,8a-dicarbonitrile, 3, is reported.Crystal data: orthorhombic, space group P212121; Z=4; a=16.059(5), b=8.920(3), c=7.592(3) Angstroem; V=1087.5 Angstroem3, Dc=1.27 g*cm-3.

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