62961-57-3 Usage
Uses
Used in Pharmaceutical Industry:
(6S)-Tetrahydro-L-biopterin is used as a cofactor in the pharmaceutical industry for the production of neurotransmitters. It is essential for the proper functioning of enzymes involved in the synthesis of catecholamines, serotonin, and nitric oxide, which are crucial for various physiological processes.
Used in Neurotransmitter Production:
(6S)-Tetrahydro-L-biopterin is used as a cofactor for the production of neurotransmitters such as catecholamines, serotonin, and nitric oxide. It plays a vital role in the synthesis of these neurotransmitters, which are essential for maintaining proper brain function and overall health.
Used in Enzyme Function:
(6S)-Tetrahydro-L-biopterin is used as a cofactor for enzymes such as phenylalanine hydroxylase, tyrosine hydroxylase, tryptophan hydroxylase, and nitric oxide synthase. It is crucial for the proper functioning of these enzymes, which are involved in various metabolic pathways and physiological processes.
Check Digit Verification of cas no
The CAS Registry Mumber 62961-57-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,9,6 and 1 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 62961-57:
(7*6)+(6*2)+(5*9)+(4*6)+(3*1)+(2*5)+(1*7)=143
143 % 10 = 3
So 62961-57-3 is a valid CAS Registry Number.
62961-57-3Relevant academic research and scientific papers
Matsuura, Sadao,Murata, Shizuaki,Sugimoto, Takashi
, p. 735 - 738 (1984)
(6R)-Tetrahydrobiopterin cofactor for aromatic amino acid hydroxylases was synthesized stereoselectively by catalytic hydrogenation of biopterin over platinum oxide at pH 11.4 and subsequent crystallization from hydrochloric acid and ethanol.
PROCESSES FOR PREPARING TETRAHYDROBIOPTERIN, AND ANALOGS OF TETRAHYDROBIOPTERIN
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Page/Page column 28-29, (2008/06/13)
Process for the preparation of tetrahydrobiopterin from neopterin and/or 6-substituted pterins with an improved yield and a high stereoselectivity. Also disclosed herein are novel individual intermediates prepared in the preparation of tetrahydrobiopterin, such as selectively protected neopterin useful for the preparation of tetrahydrobiopterin.
HYDROGENATION OF BIOPTERIN AND ITS ANALOGUES; APPLICATION FOR THE CONVENIENT PROCEDURE OF BIOPTERIN COFACTOR AND RELATED 5,6,7,8-TETRAHYDROPTERINS
Matsuura, Sadao,Murata, Shizuaki,Sugimoto, Takashi
, p. 3115 - 3120 (2007/10/02)
A large scale and stereoselective hydrogenation of biopterin to (6R)-5,6,7,8-tetrahydrobiopterin was developed.The procedure was applied for various hydroxyalkylpterins such as neopterin and diastereomers of biopterin.
