629645-73-4

Upstream product

• 629645-70-1 (2R,4aR,6S,7R,8aS)-6-((S)-1-Hydroxy-but-3-enyl)-6-methyl-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol 
• 131310-61-7 (2R,4aR,6S,7R,8aS)-6-Methyl-2-phenyl-6-vinyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol 
• 108-24-7 acetic anhydride 

Downstream Products

• 858346-44-8 2,2-Dimethyl-propionic acid (2R,3S,4aR,6R,8S,8aR)-8-acetoxy-6-[2-(tert-butyl-diphenyl-silanyloxymethyl)-allyl]-2-(2,2-dimethyl-propionyloxymethyl)-8a-methyl-octahydro-pyrano[3,2-b]pyran-3-yl ester 
• 858346-45-9 (2R,4aR,5S,7R,8aR,9aS,10aR)-5-(tert-Butyl-dimethyl-silanyloxy)-7-[2-(tert-butyl-diphenyl-silanyloxymethyl)-allyl]-2-(4-methoxy-phenyl)-10a-methyl-octahydro-1,3,8,10-tetraoxa-anthracene 
• 858346-62-0 {(2R,3S,4aR,6R,8S,8aR)-8-(tert-Butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxymethyl)-allyl]-8a-methyl-3-triethylsilanyloxy-octahydro-pyrano[3,2-b]pyran-2-yl}-acetaldehyde 
• 858346-46-0 {(2R,3S,4aR,6R,8S,8aR)-8-(tert-Butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxymethyl)-allyl]-8a-methyl-3-triethylsilanyloxy-octahydro-pyrano[3,2-b]pyran-2-yl}-acetonitrile 
• 858346-17-5 {(2R,3S,4aR,6R,8S,8aR)-8-(tert-Butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxymethyl)-allyl]-8a-methyl-3-triethylsilanyloxy-octahydro-pyrano[3,2-b]pyran-2-yl}-acetic acid 
• 630102-83-9 (2R,4aR,5S,7R,8aR,9aS,10aS)-7-Allyl-10a-methyl-2-phenyl-octahydro-1,3,8,10-tetraoxa-anthracen-5-ol 
• 629645-75-6 (2R,4aR,5S,7R,8aR,9aS,10aS)-7-Allyl-5-benzyloxy-10a-methyl-2-phenyl-octahydro-1,3,8,10-tetraoxa-anthracene 
• 629645-77-8 3-((2R,4aR,5S,7R,8aR,9aS,10aS)-5-Benzyloxy-10a-methyl-2-phenyl-octahydro-1,3,8,10-tetraoxa-anthracen-7-yl)-propan-1-ol 
• 629645-78-9 (2R,3S,4aR,6R,8S,8aS)-8-Benzyloxy-6-(3-benzyloxy-propyl)-2-hydroxymethyl-8a-methyl-octahydro-pyrano[3,2-b]pyran-3-ol 
• 630102-85-1 [(2R,3S,4aR,6R,8S,8aS)-8-Benzyloxy-6-(3-benzyloxy-propyl)-3-hydroxy-8a-methyl-octahydro-pyrano[3,2-b]pyran-2-yl]-acetonitrile 
• 629645-80-3 [(2R,3S,4aR,6R,8S,8aS)-8-Benzyloxy-6-(3-benzyloxy-propyl)-3-(tert-butyl-dimethyl-silanyloxy)-8a-methyl-octahydro-pyrano[3,2-b]pyran-2-yl]-acetonitrile 
• 629645-82-5 [(2R,3S,4aR,6R,8S,8aS)-8-Benzyloxy-6-(3-benzyloxy-propyl)-3-(tert-butyl-dimethyl-silanyloxy)-8a-methyl-octahydro-pyrano[3,2-b]pyran-2-yl]-acetic acid 
• 630102-84-0 Toluene-4-sulfonic acid (2R,3S,4aR,6R,8S,8aS)-8-benzyloxy-6-(3-benzyloxy-propyl)-3-hydroxy-8a-methyl-octahydro-pyrano[3,2-b]pyran-2-ylmethyl ester 
• 629645-84-7 [(2R,3S,4aR,6R,8S,8aS)-8-Benzyloxy-6-(3-benzyloxy-propyl)-3-hydroxy-8a-methyl-octahydro-pyrano[3,2-b]pyran-2-yl]-acetic acid (2R,4aR,6R,7S,8aR,9aS,10aS)-7-allyl-4a,7,10a-trimethyl-2-phenyl-octahydro-1,3,8,10-tetraoxa-anthracen-6-yl ester 

Relevant academic research and scientific papers

Total synthesis of brevetoxin B

The convergent total synthesis of brevetoxin B (1) has been achieved. The intramolecular allylation of the O,S-acetal 20, prepared from the α-chlorosulfide 17 and the alcohol 5, was carried out using AgOTf as a Lewis acid to give the diene 21, predominant

Convergent synthesis of the F-K ring segment of brevetoxin B

A convergent synthesis of the F-K ring segment of brevetoxin B has been achieved via the intramolecular allylation of an α-chloroacetoxy ether and subsequent ring-closing metathesis.