629655-23-8

Basic information

• Product Name: 2-CHLORO-3-NITROPYRIDIN-4-OL
• Synonyms: 2-CHLORO-3-NITROPYRIDIN-4-OL;2-Chloro-3-nitropyridin-4-ol, min. 95 %
• CAS NO: 629655-23-8
• Molecular Formula: C₅H₃ClN₂O₃
• Molecular Weight: 174.54
• Mol File: 629655-23-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 408.2 °C at 760 mmHg
• Flash Point: 200.7 °C
• Appearance: /
• Density: 1.664 g/cm³
• Refractive Index: 1.637
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -2.59±0.20(Predicted)
• CAS DataBase Reference: 2-CHLORO-3-NITROPYRIDIN-4-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-3-NITROPYRIDIN-4-OL(629655-23-8)
• EPA Substance Registry System: 2-CHLORO-3-NITROPYRIDIN-4-OL(629655-23-8)

Safety Data

• Hazardous Substances Data: 629655-23-8(Hazardous Substances Data)

Usage

General Description

2-CHLORO-3-NITROPYRIDIN-4-OL is a chemical compound with the molecular formula C5H3ClN2O3. It is a yellow solid with a molecular weight of 174.54 g/mol. 2-CHLORO-3-NITROPYRIDIN-4-OL is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It can also be used in the manufacture of dyes and pigments. 2-CHLORO-3-NITROPYRIDIN-4-OL is known for its nitro and chloro functional groups, which make it a versatile building block for various chemical reactions and organic syntheses. It is important to handle this compound with care, as it may be harmful if ingested, inhaled, or in contact with skin and eyes.

InChI:InChI=1/C5H3ClN2O3/c6-5-4(8(10)11)3(9)1-2-7-5/h1-2H,(H,7,9)

Upstream product

• 626-03-9 3-deazauracil 
• 89282-12-2 2,4-dihydroxy-3-nitropyridine 
• 5975-12-2 2,4-dichloro-3-nitro-pyridine 

Downstream Products

• 1590410-09-5 C₁₅H₁₃BrN₂O₃ 
• 1590410-10-8 C₁₄H₁₁BrN₂O₃ 
• 1590410-12-0 C₁₆H₁₅BrN₂O₄ 
• 1590410-15-3 C₂₆H₂₁F₃N₄O₅ 
• 1590410-13-1 C₂₀H₂₀N₄O₄ 
• 1590410-14-2 C₁₉H₁₈N₄O₄ 
• 1590406-96-4 C₁₈H₁₃F₃N₄O₄ 
• 1201681-60-8 8-hydroxy-1,4-dihydro-pyrido[2,3-b]pyrazine-2,3-dione 

Relevant articles and documents

PDE4 INHIBITOR

Provided are a PDE4 inhibitor and a use thereof in the preparation of a medicament for treating PDE4 related diseases. Specifically disclosed are the compound as shown in formula (I) and a pharmaceutically acceptable salt thereof.

ANTI-FIBROTIC PYRIDINONES

This application relates to polycyclic compounds with a pyridinone or pyridinone derivative core including, substituted pyridinones, 5,6- and 6,6- bicyclic heterocycles and substituted pyridine-thiones. This application also discloses methods of preparing these polycyclic compounds, pharmaceutical compositions and medicaments comprising said compounds and methods to treat, prevent or diagnose diseases, disorders or conditions associated with fibrosis.

PROCESS FOR PREPARATION OF NITROPYRIDINE DERIVATIVES

Disclosed here is a process for the preparation of nitropyridine derivatives of Formula (I) and its salt and precursors such as halogenated amino pyridines; Wherein; R1 is selected from amino group, hydroxyl group, acyl group, alkyl amino group, halogen atom, -NH - C (O) - R3; Where R3 is branched or linear alkyl group having 1 - 6 carbon atoms, or cycloalkyl group having 3 - 6 carbon atoms; R2 is selected from hydroxyl group, halogen atom, alkoxy group,