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(6-Amino-1H-indol-3-yl)acetonitrile, also known as 6-Aminoindole-3-acetonitrile, is a chemical compound with the molecular formula C10H9N3. It is a derivative of indole, a heterocyclic aromatic organic compound, and it contains an amino group and an acetonitrile group. (6-Amino-1H-indol-3-yl)acetonitrile is recognized for its potential in the synthesis of various pharmaceuticals and agrochemicals, as well as for its biological and medicinal properties, such as anti-tumor, anti-inflammatory, and anti-bacterial activities. Furthermore, it has been explored as a building block in the synthesis of novel small molecules for drug discovery and development.

629662-49-3

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629662-49-3 Usage

Uses

Used in Pharmaceutical Synthesis:
(6-Amino-1H-indol-3-yl)acetonitrile is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Production:
In the agrochemical industry, (6-Amino-1H-indol-3-yl)acetonitrile is utilized as a starting material for the creation of compounds that can be used in pest control and crop protection, leveraging its chemical properties to enhance agricultural productivity.
Used in Drug Discovery and Development:
(6-Amino-1H-indol-3-yl)acetonitrile is employed as a building block in the synthesis of novel small molecules, which are crucial for drug discovery and development. Its unique structure allows for the exploration of new chemical entities with potential medicinal value.
Used in Anti-Tumor Applications:
(6-Amino-1H-indol-3-yl)acetonitrile is used as an anti-tumor agent due to its potential to exhibit anti-cancer properties, making it a candidate for further research and development in oncology.
Used in Anti-Inflammatory and Anti-Bacterial Applications:
(6-Amino-1H-indol-3-yl)acetonitrile is also used in the development of anti-inflammatory and anti-bacterial agents, given its demonstrated biological activities that could be harnessed to treat various conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 629662-49-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,2,9,6,6 and 2 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 629662-49:
(8*6)+(7*2)+(6*9)+(5*6)+(4*6)+(3*2)+(2*4)+(1*9)=193
193 % 10 = 3
So 629662-49-3 is a valid CAS Registry Number.

629662-49-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(6-amino-1H-indol-3-yl)acetonitrile

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:629662-49-3 SDS

629662-49-3Relevant academic research and scientific papers

Compositions for Treatment of Cystic Fibrosis and Other Chronic Diseases

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, (2015/09/22)

The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.

MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS

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, (2012/12/14)

The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.

COMPOSITIONS FOR TREATMENT OF CYSTIC FIBROSIS AND OTHER CHRONIC DISEASES

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, (2012/04/23)

The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.

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