62983-64-6

Upstream product

• 103292-13-3 4-Formyl-3-hydroxyphenyl 2,3,4,6-tetra-O-acetyl-β-D-galactopyranoside 
• 74-88-4 methyl iodide 
• 95-01-2 2,4-Dihydroxybenzaldehyde 
• 19186-59-5 2,3,4,6-tetra-O-acetyl-α-D-galactopyranosyl bromide 

Downstream Products

• 103292-16-6 3-Methoxy-4-(2-nitrovinyl)phenyl β-D-galactopyranoside 
• 103292-15-5 4-Formyl-3-methoxyphenyl β-D-galactopyranoside 

Relevant academic research and scientific papers

3-Methoxy-4-(2-nitrovinyl)phenyl glycosides as potential chromogenic substrates for the assay of glycosidases.

Selective glycosidation of 2,4-dihydroxybenzaldehyde with either 2,3,4, 6-tetra-O-acetyl-alpha-D-glucopyranosyl bromide, 2-acetamido-3,4,6-tri-O-acetyl-alpha-D-glucopyranosyl chloride, or 2,3,4,6-tetra-O-acetyl-alpha-D-galactopyranosyl bromide afforded the corresponding 4-O-glycosyl derivatives. Subsequent O-methylation, O-deacetylation, and condensation with nitromethane afforded the appropriate beta-glycoside of 3-methoxy-4-(2-nitrovinyl)phenol. The phenol is highly coloured at alkaline pH so that these glycosides may be suitable as chromogenic substrates for the assay of glycosidases.