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4-Chloro-alpha-methylbenzylamine is an organic compound with the chemical formula C8H10ClN. It is a clear yellow liquid and belongs to the class of chiral amines. 4-Chloro-alpha-methylbenzylamine is characterized by the presence of a chlorine atom at the 4-position of the benzene ring and a methyl group attached to the alpha-carbon, which is the carbon atom directly attached to the benzene ring.

6299-02-1

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6299-02-1 Usage

Uses

Used in Pharmaceutical Industry:
4-Chloro-alpha-methylbenzylamine is used as an intermediate in the synthesis of various pharmaceutical compounds. Its chiral nature makes it a valuable building block for the development of enantiomerically pure drugs, which can have different biological activities and reduced side effects compared to their racemic counterparts.
Used in Enzymatic Reactions:
In the field of biochemistry, 4-Chloro-alpha-methylbenzylamine can be utilized in enantioselective acylation reactions, such as the preparation of N-phenylacetyl-(R)-1-(4-chlorophenyl)ethylamine. These reactions are often carried out in aqueous media and involve enzymes like penicillin acylase from Alcaligenes faecalis, which can selectively catalyze the acylation of the desired enantiomer, leading to a more efficient and environmentally friendly synthesis process.
Used in Chemical Research:
4-Chloro-alpha-methylbenzylamine can also be employed as a research tool in various chemical studies, including the investigation of reaction mechanisms, the development of new synthetic methods, and the exploration of novel applications in materials science, agrochemistry, and other related fields.

Check Digit Verification of cas no

The CAS Registry Mumber 6299-02-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,9 and 9 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 6299-02:
(6*6)+(5*2)+(4*9)+(3*9)+(2*0)+(1*2)=111
111 % 10 = 1
So 6299-02-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H10ClN/c1-6(10)7-2-4-8(9)5-3-7/h2-6H,10H2,1H3/p+1/t6-/m1/s1

6299-02-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Chloro-alpha-methylbenzylamine

1.2 Other means of identification

Product number -
Other names 1-(4-chlorophenyl)ethanamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6299-02-1 SDS

6299-02-1Downstream Products

6299-02-1Relevant academic research and scientific papers

OPTICALLY ACTIVE F-2-ISOPROPOXYPROPIONIC ACID: A NOVEL DERIVATIZING AGENT FOR GAS CHROMATOGRAPHIC ANALYSIS

Kawa, Hajimu,Yamaguchi, Fumihiko,Ishikawa, Nobuo

, p. 745 - 748 (2007/10/02)

F-2-Isopropoxypropionic acid (PIPA) was resolved into enantiomers via its diastereomeric (+)-1-phenylethylamide. (+)-F-2-Isopropoxypropionyl derivatives of several chiral 1-arylalkylamines and α-amino acids were effectively resolved by gas chromatography at low temperature.

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