63-98-9

Basic information

• Product Name: PHENYLACETYLUREA
• Synonyms: LABOTEST-BB LT00455073;PHENURONE;PHENYLACETYLUREA;PHENACEMIDE;PHENACETYLUREA;(phenylacetyl)-ure;A-1348;Acetylureum
• CAS NO: 63-98-9
• Molecular Formula: C₉H₁₀N₂O₂
• Molecular Weight: 178.19
• EINECS: 200-570-2
• Mol File: 63-98-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 214-216 °C
• Boiling Point: 310.41°C (rough estimate)
• Appearance: /
• Density: 1.2221 (rough estimate)
• Refractive Index: 1.5600 (estimate)
• PKA: 12.38±0.70(Predicted)
• Water Solubility: 182mg/L(temperature not stated)
• CAS DataBase Reference: PHENYLACETYLUREA(CAS DataBase Reference)
• NIST Chemistry Reference: PHENYLACETYLUREA(63-98-9)
• EPA Substance Registry System: PHENYLACETYLUREA(63-98-9)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 63-98-9(Hazardous Substances Data)

Usage

Chemical Properties

white to yellow powder

Uses

Anticonvulsant.

Brand name

Phenurone (Abbott).

Safety Profile

Moderately toxic by ingestion and intraperitoneal routes. Experimental teratogenic effects. Used as an anticonvulsive agent. When heated to decomposition it emits toxic fumes of NOx.

InChI:InChI=1/C8H8O2.CH4N2O/c9-8(10)6-7-4-2-1-3-5-7;2-1(3)4/h1-5H,6H2,(H,9,10);(H4,2,3,4)

Upstream product

• 103-80-0 phenylacetyl chloride 
• 103-82-2 phenylacetic acid 
• 4283-15-2 phenylacetylcarbamic acid ethyl ester 
• 102618-95-1 6-Benzyl-2H-1,3,5-oxadiazine-2,4(3H)-dione 
• 57-13-6 urea 
• 111155-59-0 phenylacetylcarbamic acid 

Downstream Products

• 7089-34-1 ((Z)-3-Dimethylamino-2-phenyl-allylidene)-dimethyl-ammonium; perchlorate 

Relevant articles and documents

ORGANOPHOSPHORUS COMPOUNDS XXXIX. THE ACTION OF ALKYL PHOSPHITES ON OXAZOLIDINEDIONES. A NOVEL SYNTHESIS OF CARBAMIC ACID DERIVATIVES

Depending upon the experimental conditions trimethyl-, triethyl-, and triisopropyl phosphites react with oxazolidinedione (1a) ti give acid 2a and/or the corresponding alkyl ester 2b, c.Phenylacetamide (3) is also formed in a small amount.On the other hand, trialkyl phosphites cause the quantitative conversion of dione 1b into diphenylacetamide.The identity of the new compounds is established from analytical, chemical and spectroscopic evidence.

Pharmaceutical composition and process of treatment

A process for alleviating proliferative skin diseases such as psoriasis, atopic dermatitis, etc. comprising administering to humans, or domesticated animals, topically and/or systemically a composition comprising a pharmaceutical carrier and at least one active compound selected from the groups, substituted alkyl zanthines, tricyclic antidepressants, organic nitrates, antihypertensives, anti-asthma agents and central nervous system depressants and combinations of certain compounds from specifically named groups of compounds.