6301-24-2

Usage

Structure

Long-chain, straight-chain oxazoline derivative

Usage

Emulsifier, corrosion inhibitor, surfactant, component in personal care products, stabilizer in polymer formulations

Melting point

High

Hazardous

Non-hazardous chemical

InChI:InChI=1/C20H37NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20-21-18-19-22-20/h9-10H,2-8,11-19H2,1H3

Upstream product

• 7545-20-2 N-(2-hydroxyethyl)oleamide 
• 7545-20-2 N-oleoylethanolamine 
• 2197-55-9 octadec-8-enoic acid 
• 141-43-5 ethanolamine 

Relevant academic research and scientific papers

Robust amidation transformation of plant oils into fatty derivatives for sustainable monomers and polymers

Sustainable fuels, chemicals, and materials from renewable resources have recently gained tremendous momentum in a global scale, although there are numerous nontrivial hurdles for making them more competitive with petroleum counterparts. We demonstrate a

COMPOSITIONS AND METHODS FOR THE MODULATION OF SPECIFIC AMIDASES FOR N-ACYLETHANOLAMINES FOR USE IN THE THERAPY OF INFLAMMATORY DISEASES

The present invention regards compositions and methods for the modulation of amidases capable of hydrolysing N-acylethanolamines useable in the therapy of inflammatory diseases. In particular, the present invention regards a compound of general formula (I): enantiomers, diastereoisomers, racemes and mixtures, polymorphs, salts, solvates thereof, wherein: (a) R is a linear alkyl radical having 13 to 19 carbon atoms or alkenyl radical having 13 to 19 carbon atoms carrying a double bond; (b) X is 0 or S; (c) Y is a 2 or 3 carbon atom alkylene residue, optionally substituted with one or two groups equal or different from each other and selected from among the group consisting of: -CH3, -CH2OH, -COOCH3, -COOH. Y may preferably be: -CH2-CH2-, -CH2-CH2-CH2-, CH (CH3) -CH2-, -CH2-CH (CH3) -, -CH2-C (CH3) 2-, -CH2-CH (CH2OH) -, -CH2-C ( (CH2OH) 2) -, -CH=CH-, -CH2-CH (COOCH3) -, -CH2-CH (COOH) -, for use as a medicine.

Synthesis of 2-oxazolines via boron esters of N-(2-hydroxyethyl) amides

A new, convenient, one-pot process is presented for the synthesis of 2-oxazolines in high yields (75-94%) via boron esters of N-(2-hydroxyethyl) amides. The procedure involves thermolysis of the boron esters at 240-260 °C, in the presence of solid CaO as an acid scavenger and allows the preparation of oxazolines from hydroxyethyl amides of aliphatic and aromatic monocarboxylic acids.