630129-63-4Relevant academic research and scientific papers
A short route to L-iduronic acid building blocks for the syntheses of heparin-like disaccharides
Ke, Weijun,Whitfield, Dennis M.,Gill, Manjinder,Larocque, Suzon,Yu, Siu-Hong
, p. 7767 - 7770 (2003)
The effective preparation of differentially protected L-iduronic acid derivatives, as building blocks for the synthesis of heparin-like oligosaccharides, is described in less than nine steps starting from readily available 1,2-O-isopropylidene-6,3-D-glucu
Development of specific inhibitors for heparin-binding proteins based on the cobra cardiotoxin structure: An effective synthetic strategy for rationally modified heparin-like disaccharides and a trisaccharide
Ke, Weijun,Whitfield, Dennis M.,Brisson, Jean-Robert,Enright, Gary,Jarrell, Harold C.,Wu, Wen-Guey
, p. 355 - 372 (2007/10/03)
Recently, a new heparin disaccharide-binding site on the convex side of cobra cardiotoxin (CTX) was identified by NMR spectroscopy and molecular modeling. To further characterize this site two heparin-like disaccharides were synthesized for binding studie
