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2-[(2-amino-6-methyl-pyrimidin-4-yl)-phenyl-amino]ethanol, commonly known as methyldopa, is a chemical compound with the formula C13H14N4O. It is an amino acid derivative that serves as a medication for treating high blood pressure and gestational hypertension. Methyldopa operates by stimulating alpha-adrenergic receptors in the central nervous system, which leads to a reduction in sympathetic outflow to the heart, kidneys, and peripheral vasculature, thereby decreasing total peripheral resistance and blood pressure. It is considered safe for use during pregnancy and is often the medication of choice for hypertension in pregnant women.

6303-38-4

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6303-38-4 Usage

Uses

Used in Pharmaceutical Industry:
2-[(2-amino-6-methyl-pyrimidin-4-yl)-phenyl-amino]ethanol is used as an antihypertensive agent for the treatment of high blood pressure and gestational hypertension. It is valued for its efficacy in reducing blood pressure through its action on central nervous system alpha-adrenergic receptors, leading to a decrease in sympathetic outflow and peripheral resistance.
Used in Combination Therapy:
2-[(2-amino-6-methyl-pyrimidin-4-yl)-phenyl-amino]ethanol is also used in combination with other antihypertensive medications to enhance the overall therapeutic effect on blood pressure management. This combination approach can be beneficial for patients who require additional support to achieve optimal blood pressure control.
Used in Pregnancy Care:
Methyldopa is used as a safe treatment option for pregnant women suffering from hypertension. Its safety profile during pregnancy makes it a preferred choice for managing high blood pressure in this population, ensuring both the health of the mother and the developing fetus are protected.

Check Digit Verification of cas no

The CAS Registry Mumber 6303-38-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,0 and 3 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 6303-38:
(6*6)+(5*3)+(4*0)+(3*3)+(2*3)+(1*8)=74
74 % 10 = 4
So 6303-38-4 is a valid CAS Registry Number.
InChI:InChI=1/C13H16N4O/c1-10-9-12(16-13(14)15-10)17(7-8-18)11-5-3-2-4-6-11/h2-6,9,18H,7-8H2,1H3,(H2,14,15,16)

6303-38-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(N-(2-amino-6-methylpyrimidin-4-yl)anilino)ethanol

1.2 Other means of identification

Product number -
Other names 2-Amino-6-methyl-4-<N-(2-hydroxy-aethyl)-anilino>-pyrimidin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6303-38-4 SDS

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