630384-48-4Relevant academic research and scientific papers
Highly efficacious factor Xa inhibitors containing α-substituted phenylcycloalkyl P4 moieties
Qiao, Jennifer X.,King, Sarah R.,He, Kan,Wong, Pancras C.,Rendina, Alan R.,Luettgen, Joseph M.,Xin, Baomin,Knabb, Robert M.,Wexler, Ruth R.,Lam, Patrick Y.S.
scheme or table, p. 462 - 468 (2011/03/19)
We previously disclosed a series of highly potent FXa inhibitors bearing α-substituted (CH2NR1R2) phenylcyclopropyl P4 moieties in the pyrazolodihydropyridone core system. Herein, we describe our continuous SAR efforts in
1,1-DISUBSTITUTED CYCLOALKYL DERIVATIVES AS FACTOR XA INHIBITORS
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Page 400-401, (2010/02/05)
The present application describes 1,1-disubstituted cycloalkyl compounds and derivatives thereof, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of factor Xa.
