630385-56-7

Upstream product

• 84542-11-0 2-(4-formylphenyl)-2-methylpropionic acid methyl ester 
• 201230-82-2 carbon monoxide 
• 154825-97-5 methyl 2-(4-bromophenyl)-2,2-dimethylacetate 
• 630385-42-1 methyl 2-(4-chlorocarbonylphenyl)-2-methylpropanoate 

Downstream Products

• 630385-42-1 methyl 2-(4-chlorocarbonylphenyl)-2-methylpropanoate 
• 630385-57-8 2-(4-hydroxymethylphenyl)-2-methylpropionic acid methyl ester 
• 916343-03-8 4-[4-(1-methoxycarbonyl-1-methyl-ethyl)-benzoylamino]-piperidine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Imidazopyridine and Pyrazolopiperidine Derivatives as Novel Inhibitors of Serine Palmitoyl Transferase

To develop novel treatments for type 2 diabetes and dyslipidemia, we pursued inhibitors of serine palmitoyl transferase (SPT). To this end compounds 1 and 2 were developed as potent SPT inhibitors in vitro. 1 and 2 reduce plasma ceramides in rodents, have

INTERMEDIATES USEFUL FOR THE PREPARATION OF ANTIHISTAMINIC PIPERIDINE DERIVATIVE

The present invention relates to process for preparing antihistaminic piperidine derivative, specifically fexofenadine and its pharmaceutically acceptable salts by using novel synthetic intermediates of following formula (I), wherein R is lower alkyl; R2 is H, cyclopropyl, R1is alkyl, 4-(hydroxy-dipheτiyl-methyl)-piperidin-l-yl.

Amide derivatives as somatostatin receptor 5 antagonists

This invention is concerned with compounds of the formula wherein R1 to R5, R5′ and A are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.

1,1-DISUBSTITUTED CYCLOALKYL DERIVATIVES AS FACTOR XA INHIBITORS

The present application describes 1,1-disubstituted cycloalkyl compounds and derivatives thereof, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of factor Xa.