630400-87-2

Upstream product

• 135582-93-3 (S)-3-[N-(benzyloxycarbonyl)amino]-1,2-propanediol 
• 77-76-9 2,2-dimethoxy-propane 
• 630400-86-1 Toluene-4-sulfonic acid (S)-3-benzyloxycarbonylamino-2-hydroxy-propyl ester 

Downstream Products

• 630400-88-3 (5S)-N-benzyloxycarbonyl-5-iodomethyl oxazolidine 

Relevant academic research and scientific papers

Asymmetric synthesis of orthogonally protected (2S,4R)- and (2S,4S)-4-hydroxyornithine

Synthesis of orthogonally protected (2S, 4R)- and (2S, 4S)-4-hydroxyornithine was reported featuring an asymmetric alkylation of N-(diphenylmethylene)glycine tert-butyl ester (6) by (5S)-N-benzyloxycarbonyl-5-iodomethyl oxazolidine (7). Double stereoselection was examined using chiral ammonium salts as phase transfer catalysts and a substrate-directed chiral induction is documented.