630404-09-0

Basic information

• Product Name: 4-CHLORO-3-(TRIFLUOROMETHYL)PHENACYL BROMIDE
• Synonyms: 4-CHLORO-3-(TRIFLUOROMETHYL)PHENACYL BROMIDE;2-Bromo-4'-chloro-3'-(trifluoromethyl)acetophenone;2-Bromo-4'-chloro-3'-(trifluoromethyl)acetophenone, 2-Bromo-1-[4-chloro-3-(trifluoromethyl)phenyl]ethan-1-one, 5-(Bromoacetyl)-2-chlorobenzotrifluoride;2-bromo-1-(4-chloro-3-(trifluoromethyl)phenyl)ethanone
• CAS NO: 630404-09-0
• Molecular Formula: C₉H₅BrClF₃O
• Molecular Weight: 301.49
• Mol File: 630404-09-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-CHLORO-3-(TRIFLUOROMETHYL)PHENACYL BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-3-(TRIFLUOROMETHYL)PHENACYL BROMIDE(630404-09-0)
• EPA Substance Registry System: 4-CHLORO-3-(TRIFLUOROMETHYL)PHENACYL BROMIDE(630404-09-0)

Safety Data

• Hazard Codes: C
• Hazardous Substances Data: 630404-09-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-CHLORO-3-(TRIFLUOROMETHYL)PHENACYL BROMIDE is used as a key intermediate for the synthesis of various pharmaceutical compounds. Its electron-withdrawing trifluoromethyl group and reactivity due to chloro and bromo groups make it suitable for the development of new drugs with improved properties.
Used in Agrochemical Industry:
4-CHLORO-3-(TRIFLUOROMETHYL)PHENACYL BROMIDE is used as a building block in the synthesis of agrochemicals. Its versatile chemical structure allows for the creation of new compounds with potential applications in agriculture, such as pesticides and herbicides.
Used in Organic Synthesis:
4-CHLORO-3-(TRIFLUOROMETHYL)PHENACYL BROMIDE is used as a versatile intermediate in organic synthesis. Its unique structure and reactivity make it a valuable tool for the development of new compounds with a wide range of applications in various industries.

Upstream product

• 129825-11-2 1-(4-chloro-3-(trifluoromethyl)phenyl)ethanone 

Downstream Products

• 1584670-73-4 2-bromo-1-(4-chloro-3-(trifluoromethyl)phenyl)ethanol 
• 952737-21-2 4-(4-{2-[4-chloro-3-(trifluoromethyl)phenyl]-2-oxoethyl}-3-oxo-1,4-diazaspiro[4.4]non-1-en-2-yl)benzonitrile 

Relevant articles and documents

DIHYDROOXADIAZINONES

The present invention provides dihydrooxydiazinone compounds of general formula (I) : in which R1, R2, R3, and R4, are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative diseases, as a sole agent or in combination with other active ingredients.

DERIVATIVES OF BENZOTHIAZINES, PREPARATION THEREOF AND APPLICATION THEREOF AS DRUGS

The object of the present invention is benzothiazine derivatives having the capability of inhibiting 11β-HSD1 not only at an enzymatic level but also at a cell level. The compounds of the present invention are of general formula (I). Wherein notably R1 represents a hydrogen or OR1 represents an ester or an ether. R2 represents a naphthyl or a 1, 2, 3, 4-tetrahydro-naphthalene or a biphenyl or phenyl pyridine or a substituted phenyl. R3 represents a methyl or ethyl; R4 and R'4 represent a hydrogen.

DIHYDROIMIDAZOTHIAZOLE DERIVATIVES

Compounds of formula (I): or pharmaceutically acceptable salts thereof, exhibit 5-HT1A agonism in addition to noradrenaline reuptake inhibition and optionally also 5-HT reuptake inhibition are useful for the treatment of obesity.

IMIDAZOLIUM CXCR3 INHIBITORS

Imidazolium compounds of formula (I); wherein: Aˉ is an anion; R1, R2 and R3 are the same or different and are hydrogen, C1-C6 alkyl, aryl, fused aryl, or heteroaryl; or are substituted aryl, fused ar