630416-37-4

Basic information

• Product Name: 4-Bromo-6-phenylpyridazin-3-amine
• Synonyms: 4-Bromo-6-phenylpyridazin-3-amine
• CAS NO: 630416-37-4
• Molecular Weight: 250.098
• Mol File: 630416-37-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-Bromo-6-phenylpyridazin-3-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromo-6-phenylpyridazin-3-amine(630416-37-4)
• EPA Substance Registry System: 4-Bromo-6-phenylpyridazin-3-amine(630416-37-4)

Safety Data

• Hazardous Substances Data: 630416-37-4(Hazardous Substances Data)

Upstream product

• 98-80-6 phenylboronic acid 
• 14966-91-7 3-amino-6-phenylpyridazine 
• 1074-12-0 phenylglyoxal hydrate 
• 630416-33-0 (2,4-dimethoxy-benzyl)-(4-nitro-6-phenyl-pyridazin-3-yl)-amine 

Downstream Products

• 1431772-63-2 N-(6-(2-methylpiperidin-1-yl)pyridin-2-yl)-6-phenylimidazo[1,2-b]pyridazin-8-amine 
• 1562399-00-1 1,1,1-trifluoro-4-(5-fluoro-2-methylphenyl)-4-methyl-2-(3-phenyl-7H-pyrrolo[2,3-c]pyridazin-6-ylmethyl)pentan-2-ol 
• 1562398-99-5 1-(3-amino-6-phenylpyridazin-4-yl)-6-(5-fluoro-2-methylphenyl)-6-methyl-4-trifluoromethylhept-1-yn-4-ol 
• 1431772-85-8 N-(6-(2-(methoxymethyl)pyrrolidin-1-yl)pyridin-2-yl)-6-phenylimidazo[1,2-b]pyridazin-8-amine hydrochloride 
• 1431772-82-5 N-(6-(2,2-dimethylpyrrolidin-1-yl)pyridin-2-yl)-6-phenylimidazo[1,2-b]pyridazin-8-amine hydrochloride 
• 1431772-81-4 (1-(6-(6-phenylimidazo[1,2-b]pyridazin-8-ylamino)pyridin-2-yl)pyrrolidin-2-yl)methanol hydrochloride 
• 1431772-80-3 N-(6-(2-ethylpyrrolidin-1-yl)pyridin-2-yl)-6-phenylimidazo[1,2-b]pyridazin-8-amine hydrochloride 
• 1431772-79-0 N-(6-(2,5-dimethylpyrrolidin-1-yl)pyridin-2-yl)-6-phenylimidazo[1,2-b]pyridazin-8-amine hydrochloride 
• 1431773-73-7 8-bromo-6-phenylimidazo[1,2-b]pyridazine 
• 1431772-94-9 N-(5,6-dimethoxypyridin-2-yl)-6-phenylimidazo[1,2-b]pyridazin-8-amine 
• 1431772-93-8 (S)-N-(6-(2-methylpyrrolidin-1-yl)pyridin-2-yl)-6-phenylimidazo[1,2-b]pyridazin-8-amine 
• 1431772-84-7 N-(6-(3,3-dimethylpyrrolidin-1-yl)pyridin-2-yl)-6-phenylimidazo[1,2-b]pyridazin-8-amine 
• 1431772-71-2 (R)-N-(6-(2-methylpyrrolidin-1-yl)pyridin-2-yl)-6-phenylimidazo[1,2-b]pyridazin-8-amine 
• 17258-23-0 3-amino-4,6-diphenylpyridazine 

Relevant articles and documents

IMIDAZOPYRIDAZINE COMPOUNDS

The present invention relates to the use of novel compounds of formula I: wherein all variable substituents are defined as described herein, which are SYK inhibitors and are useful for the treatment of auto-immune and inflammatory diseases.

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The invention relates to diazaindole derivatives represented by the general formula (I): where A, E, G, R1, R2, R3 and R4 are defined herein, or pharmaceutically acceptable salts thereof, their use in the inhibition of c-Jun N-terminal kinase (JNK) activity, their use in medicine and particularly in the treatment of neurodegenerative disorders, inflammatory diseases, autoimmune diseases and/or organ failure. The invention also provides processes for the manufacture of said diazaindole derivatives and compositions containing them.