630422-65-0

Usage

Properties

1. Molecular Formula: C11H9N3O
2. Derivative of acryloyl azide
3. Contains a tolyl group and an acryloyl group attached to the azide functional group
4. Used in bioconjugation chemistry and click chemistry
5. Reactive intermediate for modification of biomolecules and synthesis of diverse chemical structures
6. Versatile reactivity
7. Potential applications in pharmaceuticals, materials science, and biochemistry

Specific Content

Used in chemical reactions to introduce azide groups into molecules
Employed in bioconjugation chemistry and click chemistry
Potential uses in pharmaceuticals, materials science, and biochemistry
Reactive intermediate for modifying biomolecules
Can be used for chemical synthesis and molecular engineering

Upstream product

• 620-23-5 m-tolyl aldehyde 
• 3029-79-6 (E)-3-methylcinnamic acid 

Relevant academic research and scientific papers

Chiral phosphoric acid catalyzed enantioselective annulation of acyclic enecarbamates to: In situ -generated ortho -quinone methides

The first organocatalytic asymmetric reaction of acyclic enecarbamates with o-quinone methides is disclosed. BINOL-based phosphoric acid catalysts were found to be suitable for the annulation reaction. With 10 mol% of the TRIP catalyst, high yields as well as excellent diastereo- and enantioselectivities are achieved for a variety of 2,3,4-trisubstituted chroman products.

HEPATITIS C VIRUS INHIBITORS

Hepatitis C virus inhibitors are disclosed having the general formula:(I) wherein R1, R2, R3, R', B, Y and X are described in the description. Compositions comprising the compounds and methods for using the compounds toinhibit HCV are also disclosed.

Synthesis of novel substituted isoquinolones

A series of novel substituted isoquinolones have been synthesised. This has been achieved by two routes, either Curtius rearrangment of cinnamic acids or via an isoquinoline N-oxide.