630424-73-6 Usage
Description
BOC-(2S,3S)-2-AMINO-3-METHOXYBUTANOIC ACID is a chemical compound with the molecular formula C10H19NO4. It is a derivative of 2-amino-3-methoxybutanoic acid and is commonly used in the synthesis of pharmaceuticals and other organic compounds. BOC-(2S,3S)-2-AMINO-3-METHOXYBUTANOIC ACID contains a BOC (tert-butoxycarbonyl) protective group, which allows for selective modification of the molecule during chemical reactions. BOC-(2S,3S)-2-AMINO-3-METHOXYBUTANOIC ACID is a white solid that is stable under normal conditions and has a variety of potential applications in medicinal chemistry and drug development.
Uses
Used in Pharmaceutical Industry:
BOC-(2S,3S)-2-AMINO-3-METHOXYBUTANOIC ACID is used as a building block for the synthesis of various pharmaceuticals and organic compounds. Its BOC protective group enables selective modification of the molecule during chemical reactions, making it a valuable intermediate in the development of new drugs and therapeutic agents.
Used in Medicinal Chemistry:
BOC-(2S,3S)-2-AMINO-3-METHOXYBUTANOIC ACID is used as a research tool in medicinal chemistry for the study and development of novel drug candidates. Its unique structure and properties allow researchers to explore its potential as a precursor or component in the design of new therapeutic agents.
Used in Drug Development:
BOC-(2S,3S)-2-AMINO-3-METHOXYBUTANOIC ACID is used in drug development as a key intermediate in the synthesis of potential drug candidates. Its versatility and stability make it an attractive option for the development of new pharmaceuticals with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 630424-73-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,3,0,4,2 and 4 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 630424-73:
(8*6)+(7*3)+(6*0)+(5*4)+(4*2)+(3*4)+(2*7)+(1*3)=126
126 % 10 = 6
So 630424-73-6 is a valid CAS Registry Number.
630424-73-6Relevant articles and documents
KCNT1 INHIBITORS AND METHODS OF USE
-
, (2020/11/23)
The present invention is directed to, in part, compounds and compositions useful for preventing and/or treating a neurological disease or disorder, a disease or condition relating to excessive neuronal excitability, and/or a gain-of-function mutation in a gene (e.g., KCNT1). Methods of treating a neurological disease or disorder, a disease or condition relating to excessive neuronal excitability, and/or a gain-of-function mutation in a gene such as KCNT1 are also provided herein.
Structure-based design of highly selective β-secretase inhibitors: Synthesis, biological evaluation, and protein-ligand x-ray crystal structure
Ghosh, Arun K.,Venkateswara Rao, Kalapala,Yadav, Navnath D.,Anderson, David D.,Gavande, Navnath,Huang, Xiangping,Terzyan, Simon,Tang, Jordan
, p. 9195 - 9207,13 (2020/10/15)
The structure-based design, synthesis, and X-ray structure of protein-ligand complexes of exceptionally potent and selective β-secretase inhibitors are described. The inhibitors are designed specifically to interact with S1′ active site residues to provide selectivity over memapsin 1 and cathepsin D. Inhibitor 5 has exhibited exceedingly potent inhibitory activity (Ki = 17 pM) and high selectivity over BACE 2 (>7000-fold) and cathepsin D (>250000-fold). A protein-ligand crystal structure revealed important molecular insight into these selectivities. These interactions may serve as an important guide to design selectivity over the physiologically important aspartic acid proteases.
